Zahedan Journal of Research in Medical Sciences

Published by: Kowsar

Effect of coenzyme Q10 Supplementation on Exercise-Induced Response of Oxidative Stress and Muscle Damage Indicators in Male Runners

Mostafa Armanfar 1 , * , Afshar Jafari 1 and Gholam Reza Dehghan 2
Authors Information
1 Department of Sport Physiology, Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, IR Iran
2 Department of Biochemistry, Faculty of Natural Sciences, University of Tabriz, Tabriz, IR Iran
Article information
  • Zahedan Journal of Research in Medical Sciences: August 28, 2015, 17 (8); e1023
  • Published Online: August 29, 2015
  • Article Type: Research Article
  • Received: April 28, 2014
  • Accepted: June 10, 2014
  • DOI: 10.17795/zjrms1023

To Cite: Armanfar M, Jafari A, Dehghan G R. Effect of coenzyme Q10 Supplementation on Exercise-Induced Response of Oxidative Stress and Muscle Damage Indicators in Male Runners, Zahedan J Res Med Sci. 2015 ; 17(8):e1023. doi: 10.17795/zjrms1023.

Abstract
Copyright © 2015, Zahedan University of Medical Sciences.This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Materials and Methods
3. Results
4. Discussion
Acknowledgements
Footnotes
References
  • 1. Liu CC, Huang CC, Lin WT, Hsieh CC, Huang SY, Lin SJ, et al. Lycopene supplementation attenuated xanthine oxidase and myeloperoxidase activities in skeletal muscle tissues of rats after exhaustive exercise. Br J Nutr. 2005; 94(4): 595-601[PubMed]
  • 2. Wu HJ, Chen KT, Shee BW, Chang HC, Huang YJ, Yang RS. Effects of 24 h ultra-marathon on biochemical and hematological parameters. World J Gastroenterol. 2004; 10(18): 2711-4[PubMed]
  • 3. Kon M, Kimura F, Akimoto T, Tanabe K, Murase Y, Ikemune S, et al. Effect of coenzyme Q10 supplementation on exercise-induced muscular injury of rats. Exerc Immunol Rev. 2007; 13: 76-88[PubMed]
  • 4. Powers SK, Jackson MJ. Exercise-induced oxidative stress: cellular mechanisms and impact on muscle force production. Physiol Rev. 2008; 88(4): 1243-76[DOI][PubMed]
  • 5. Diaz-Castro J, Guisado R, Kajarabille N, Garcia C, Guisado IM, de Teresa C, et al. Coenzyme Q(10) supplementation ameliorates inflammatory signaling and oxidative stress associated with strenuous exercise. Eur J Nutr. 2012; 51(7): 791-9[DOI][PubMed]
  • 6. Vina J, Gomez-Cabrera MC, Lloret A, Marquez R, Minana JB, Pallardo FV, et al. Free radicals in exhaustive physical exercise: mechanism of production, and protection by antioxidants. IUBMB Life. 2000; 50(4-5): 271-7[DOI][PubMed]
  • 7. Jackson M. Antioxidants, reactive oxygen and nitrogen species, gene induction and mitochondrial function. Mol Aspects 2002; 23(1-3): 209-85
  • 8. Kumar CT, Reddy VK, Prasad M, Thyagaraju K, Reddanna P. Dietary supplementation of vitamin E protects heart tissue from exercise-induced oxidant stress. Mol Cell Biochem. 1992; 111(1-2): 109-15[PubMed]
  • 9. Mastaloudis A, Morrow JD, Hopkins DW, Devaraj S, Traber MG. Antioxidant supplementation prevents exercise-induced lipid peroxidation, but not inflammation, in ultramarathon runners. Free Radic Biol Med. 2004; 36(10): 1329-41[DOI][PubMed]
  • 10. Kaikkonen J, Tuomainen TP, Nyyssonen K, Salonen JT. Coenzyme Q10: absorption, antioxidative properties, determinants, and plasma levels. Free Radic Res. 2002; 36(4): 389-97[PubMed]
  • 11. Shimomura Y, Suzuki M, Sugiyama S, Hanaki Y, Ozawa T. Protective effect of coenzyme Q10 on exercise-induced muscular injury. Biochem Biophys Res Commun. 1991; 176(1): 349-55
  • 12. Zhou S, Zhang Y, Davie A, Marshall-Gradisnik S, Hu H, Wang J, et al. Muscle and plasma coenzyme Q10 concentration, aerobic power and exercise economy of healthy men in response to four weeks of supplementation. J Sports Med Phys Fitness. 2005; 45(3): 337-46[PubMed]
  • 13. Cooke M, Iosia M, Buford T, Shelmadine B, Hudson G, Kerksick C, et al. Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. J Int Soc Sports Nutr. 2008; 5: 8[DOI][PubMed]
  • 14. Dwyer GB, Davis SE. ACSM's health related physical fitness assessment manual. 2008;
  • 15. Gibson RS. Principles of nutritional assessment. 2005;
  • 16. Leelarungrayub D, Sawattikanon N, Klaphajone J, Pothongsunan P, Bloomer RJ. Coenzyme Q10 Supplementation Decreases Oxidative Stress and Improves Physical Performance in Young Swimmers: A Pilot Study. Open Sport Med J. 2010; 4(1): 1-8
  • 17. Tauler P, Ferrer MD, Sureda A, Pujol P, Drobnic F, Tur JA, et al. Supplementation with an antioxidant cocktail containing coenzyme Q prevents plasma oxidative damage induced by soccer. Eur J Appl Physiol. 2008; 104(5): 777-85[DOI][PubMed]
  • 18. Bloomer RJ, Goldfarb AH, Wideman L, McKenzie MJ, Consitt LA. Effects of acute aerobic and anaerobic exercise on blood markers of oxidative stress. J Strength Cond Res. 2005; 19(2): 276-85[DOI][PubMed]
  • 19. ACSM's health-related physical fitness assessment manual. 2013;
  • 20. Turunen M, Olsson J, Dallner G. Metabolism and function of coenzyme Q. Biochim Biophys Acta. 2004; 1660(1-2): 171-99[PubMed]
  • 21. Kagan V, Serbinova E, Packer L. Antioxidant effects of ubiquinones in microsomes and mitochondria are mediated by tocopherol recycling. Biochem Biophys Res Commun. 1990; 169(3): 851-7[DOI]
  • 22. Portakal O, İnal-Erden M. Effects of pentoxifylline and coenzyme Q10 in hepatic ischemia/reperfusion injury. Clinl Biochem. 1999; 32(6): 461-6[DOI]
  • 23. Schroder H, Navarro E, Tramullas A, Mora J, Galiano D. Nutrition antioxidant status and oxidative stress in professional basketball players: effects of a three compound antioxidative supplement. Int J Sports Med. 2000; 21(2): 146-50[DOI][PubMed]
  • 24. Gomez-Cabrera MC, Borras C, Pallardo FV, Sastre J, Ji LL, Vina J. Decreasing xanthine oxidase-mediated oxidative stress prevents useful cellular adaptations to exercise in rats. J Physiol. 2005; 567: 113-20[DOI][PubMed]
  • 25. Jackson MJ. Free radicals in skin and muscle: damaging agents or signals for adaptation? Proc Nutr Soc. 1999; 58(3): 673-6[PubMed]
  • 26. Reid MB. Invited review: redox modulation of skeletal muscle contraction: what we know and what we don't. J Appl Physiol (1985). 2001; 90(2): 724-31[PubMed]
  • 27. Goto S, Radak Z. Hormetic effects of reactive oxygen species by exercise: a view from animal studies for successful aging in human. Dose Response. 2009; 8(1): 68-72[DOI][PubMed]
  • 28. Radák Z, Kaneko T, Tahara S, Nakamoto H, Ohno H, Sasvári M, et al. The effect of exercise training on oxidative damage of lipids, proteins, and DNA in rat skeletal muscle: evidence for beneficial outcomes. Free Radic Biol Med. 1999; 27(1-2): 69-74[DOI]
  • 29. Radak Z, Sasvari M, Nyakas C, Pucsok J, Nakamoto H, Goto S. Exercise preconditioning against hydrogen peroxide-induced oxidative damage in proteins of rat myocardium. Arch Biochem Biophys. 2000; 376(2): 248-51[DOI][PubMed]
  • 30. Ochoa JJ, Quiles JL, Huertas JR, Mataix J. Coenzyme Q10 protects from aging-related oxidative stress and improves mitochondrial function in heart of rats fed a polyunsaturated fatty acid (PUFA)-rich diet. J Gerontol A Biol Sci Med Sci. 2005; 60(8): 970-5[PubMed]
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