Zahedan Journal of Research in Medical Sciences

Published by: Kowsar

The Effect of Intraventricular Administration of Zinc on Serum LH, FSH, Prolactin, and Testosterone in Male Rats

Mohammad Reza Shahraki 1 , * , Tayyebe Forghani 1 , Mehdi Mohammadi 2 and Abdurrashid Khazaei-Feizalabad 3
Authors Information
1 Department of Physiology, Zahedan University of Medical Sciences, Zahedan, IR Iran
2 Department of Statistics and Epidemiology, Faculty of Health, Zahedan University of Medical Sciences, Zahedan, IR Iran
3 Department of English, Zahedan University of Medical Sciences, Zahedan, IR Iran
Article information
  • Zahedan Journal of Research in Medical Sciences: September 28, 2015, 17 (9); e1059
  • Published Online: September 26, 2015
  • Article Type: Research Article
  • Received: June 30, 2014
  • Accepted: August 5, 2014
  • DOI: 10.17795/zjrms-1059

To Cite: Shahraki M R, Forghani T, Mohammadi M, Khazaei-Feizalabad A. The Effect of Intraventricular Administration of Zinc on Serum LH, FSH, Prolactin, and Testosterone in Male Rats, Zahedan J Res Med Sci. 2015 ; 17(9):e1059. doi: 10.17795/zjrms-1059.

Abstract
Copyright © 2015, Zahedan University of Medical Sciences.This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Boran C, Ozkan KU. The effect of zinc therapy on damaged testis in pre-pubertal rats. Pediatr Surg Int. 2004; 20(6): 444-8[DOI][PubMed]
  • 2. Sankavaram K, Chong L, Bruno RS, Freake HC. Zinc status alters growth and oxidative stress responses in rat hepatoma cells. Nutr Cancer. 2014; 66(1): 104-16[DOI][PubMed]
  • 3. Karol N, Brodski C, Bibi Y, Kaisman T, Forberg M, Hershfinkel M, et al. Zinc homeostatic proteins in the CNS are regulated by crosstalk between extracellular and intracellular zinc. J Cell Physiol. 2010; 224(3): 567-74[DOI][PubMed]
  • 4. Ranaldi G, Perozzi G, Truong-Tran A, Zalewski P, Murgia C. Intracellular distribution of labile Zn(II) and zinc transporter expression in kidney and MDCK cells. Am J Physiol Renal Physiol. 2002; 283(6)-75[DOI][PubMed]
  • 5. Hambidge KM, Krebs NF. Zinc deficiency: a special challenge. J Nutr. 2007; 137(4): 1101-5[PubMed]
  • 6. da Silva R, dos Santos-Valente EC, Burim Scomparini F, Saccardo Sarni RO, Costa-Carvalho BT. The relationship between nutritional status, vitamin A and zinc levels and oxidative stress in patients with ataxia-telangiectasia. Allergol Immunopathol (Madr). 2014; 42(4): 329-35[DOI][PubMed]
  • 7. Ott ES, Shay NF. Zinc deficiency reduces leptin gene expression and leptin secretion in rat adipocytes. Exp Biol Med (Maywood). 2001; 226(9): 841-6[PubMed]
  • 8. Fukushima T, Tan X, Luo Y, Kanda H. Serum vitamins and heavy metals in blood and urine, and the correlations among them in Parkinson's disease patients in China. Neuroepidemiology. 2011; 36(4): 240-4[DOI][PubMed]
  • 9. Krebs N, Langkammer C, Goessler W, Ropele S, Fazekas F, Yen K, et al. Assessment of trace elements in human brain using inductively coupled plasma mass spectrometry. J Trace Elem Med Biol. 2014; 28(1): 1-7[DOI][PubMed]
  • 10. Panayi AE, Spyrou NM, Iversen BS, White MA, Part P. Determination of cadmium and zinc in Alzheimer's brain tissue using inductively coupled plasma mass spectrometry. J Neurol Sci. 2002; 195(1): 1-10[PubMed]
  • 11. Blundell R, Adam F. Haemolytic anaemia and acute pancreatitis associated with zinc toxicosis in a dog. Vet Rec. 2013; 172(1): 17[DOI][PubMed]
  • 12. Mocchegiani E, Bertoni-Freddari C, Marcellini F, Malavolta M. Brain, aging and neurodegeneration: role of zinc ion availability. Prog Neurobiol. 2005; 75(6): 367-90[DOI][PubMed]
  • 13. Iguchi K, Usui S, Inoue T, Sugimura Y, Tatematsu M, Hirano K. High-level expression of zinc transporter-2 in the rat lateral and dorsal prostate. J Androl. 2002; 23(6): 819-24[PubMed]
  • 14. Martin GB, White CL, Markey CM, Blackberry MA. Effects of dietary zinc deficiency on the reproductive system of young male sheep: testicular growth and the secretion of inhibin and testosterone. J Reprod Fertil. 1994; 101(1): 87-96[PubMed]
  • 15. Dissanayake D, Wijesinghe PS, Ratnasooriya WD, Wimalasena S. Effects of zinc supplementation on sexual behavior of male rats. J Hum Reprod Sci. 2009; 2(2): 57-61[DOI][PubMed]
  • 16. Madureira G, Bloise W, Mendonca BB, Brandao-Neto J. Effect of acute and chronic oral zinc administration in hyperprolactinemic patients. Met Based Drugs. 1999; 6(3): 159-62[DOI][PubMed]
  • 17. Kim JS, Yun CH. Inhibition of human cytochrome P450 3A4 activity by zinc(II) ion. Toxicol Lett. 2005; 156(3): 341-50[DOI][PubMed]
  • 18. Daniels WM, Hendricks J, Salie R, van Rensburg SJ. A mechanism for zinc toxicity in neuroblastoma cells. Metab Brain Dis. 2004; 19(1-2): 79-88[PubMed]
  • 19. Karaca Z, Tanriverdi F, Kurtoglu S, Tokalioglu S, Unluhizarci K, Kelestimur F. Pubertal arrest due to Zn deficiency: the effect of zinc supplementation. Hormones (Athens). 2007; 6(1): 71-4[PubMed]
  • 20. Kochman K, Gajewska A, Kozlowski H, Masiukiewicz E, Rzeszotarska B. Increased LH and FSH release from the anterior pituitary of ovariectomized rat, in vivo, by copper-, nickel-, and zinc-LHRH complexes. J Inorg Biochem. 1992; 48(1): 41-6[PubMed]
  • 21. Jeong SW, Park BG, Park JY, Lee JW, Lee JH. Divalent metals differentially block cloned T-type calcium channels. Neuroreport. 2003; 14(11): 1537-40[DOI][PubMed]
  • 22. Magistretti J, Castelli L, Taglietti V, Tanzi F. Dual effect of Zn2+ on multiple types of voltage-dependent Ca2+ currents in rat palaeocortical neurons. Neuroscience. 2003; 117(2): 249-64[PubMed]
  • 23. Paxinos G, Watson C. The rat brain in stereotaxic coordinates. 2007;
  • 24. Yu L, Jiang R, Su Q, Yu H, Yang J. Hippocampal neuronal metal ion imbalance related oxidative stress in a rat model of chronic aluminum exposure and neuroprotection of meloxicam. Behav Brain Funct. 2014; 10: 6[DOI][PubMed]
  • 25. Hsieh H, Amlal H, Genter MB. Evaluation of the toxicity of zinc in the rat olfactory neuronal cell line, Odora. Hum Exp Toxicol. 2015; 34(3): 308-14[DOI][PubMed]
  • 26. Baraka AM, Hassab El Nabi W, El Ghotni S. Investigating the role of zinc in a rat model of epilepsy. CNS Neurosci Ther. 2012; 18(4): 327-33[DOI][PubMed]
  • 27. Saint Pol P, Hermand E, Tramu G. Paracrine factors in adult rat testis gonadotrophin control of opioids and LHRH like peptide. Andrologia. 1988; 20(2): 173-81[PubMed]
  • 28. Hirasawa H, Betensky RA, Raviola E. Corelease of dopamine and GABA by a retinal dopaminergic neuron. J Neurosci. 2012; 32(38): 13281-91[DOI][PubMed]
  • 29. Marubayashi U, Yu WH, McCann SM. Median eminence lesions reveal separate hypothalamic control of pulsatile follicle-stimulating hormone and luteinizing hormone release. Proc Soc Exp Biol Med. 1999; 220(3): 139-46[PubMed]
  • 30. Wilding JP. Neuropeptides and appetite control. Diabet Med. 2002; 19(8): 619-27[PubMed]
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