Zahedan Journal of Research in Medical Sciences

Published by: Kowsar

Acute Lymphoblastic Leukemia in Two Patients with β-Thalassemia Major

Majid Naderi 1 , Ebrahim Miri Moghaddam 2 , * , Shaban Alizadeh 3 , Akbar Dorgalaleh 3 and Shadi Tabibian 3
Authors Information
1 Department of Pediatrics, Research Center for Children and Adolescents Health, Zahedan University of Medical Sciences, Zahedan, Iran
2 Department of Genetics, Genetics of Non-Communicable Disease Research Centre, Zahedan University of Medical Sciences, Zahedan, Iran
3 Department of Hematology, Tehran University of Medical Sciences, Tehran, Iran
Article information
  • Zahedan Journal of Research in Medical Sciences: November 28, 2014, 16 (11); 50-51
  • Published Online: December 16, 2013
  • Article Type: Case Report
  • Received: April 23, 2013
  • Accepted: June 12, 2013

To Cite: Naderi M, Miri Moghaddam E, Alizadeh S, Dorgalaleh A, Tabibian S. Acute Lymphoblastic Leukemia in Two Patients with β-Thalassemia Major, Zahedan J Res Med Sci. 2014 ; 16(11):50-51.

Copyright © 2014 Zahedan University of Medical Sciences. All rights reserved.This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
Case Presentation
  • 1. Galanello R, Origa R. Beta-thalassemia. Orphanet J Rare Dis. 2010; 5: 11[DOI][PubMed]
  • 2. Russo A, Schiliro G. Thalassemia major and malignancies. Am J Hematol. 1987; 24(1): 111-2[PubMed]
  • 3. Farmakis D, Giakoumis A, Polymeropoulos E, Aessopos A. Pathogenetic aspects of immune deficiency associated with beta-thalassemia. Med Sci Monit. 2003; 9(1)-22[PubMed]
  • 4. Voskaridou E, Terpos E, Komninaka V, Eftyhiadis E, Mantzourani M, Loukopoulos D. Chronic myeloid leukaemia with marked thrombocytosis in a patient with thalassaemia major: complete haematological remission under the combination of hydroxyurea and anagrelide. Br J Haematol. 2002; 116(1): 155-7[PubMed]
  • 5. Lau B, Eife R, Lampert F. [Acute lymphoblastic leukemia after tuberculosis in a 8-year old greek boy with homozygous beta-thalassemia (author's transl)]. Klin Padiatr. 1975; 187(4): 357-60[PubMed]
  • 6. Zurlo MG, De Stefano P, Borgna-Pignatti C, Di Palma A, Piga A, Melevendi C, et al. Survival and causes of death in thalassaemia major. Lancet. 1989; 2(8653): 27-30[PubMed]
  • 7. Otrock ZK, Shamseddine AI, Taher AT. Non-Hodgkin disease in beta-thalassemia major. Am J Hematol. 2006; 81(1): 62-4[DOI][PubMed]
  • 8. Stevens RG, Graubard BI, Micozzi MS, Neriishi K, Blumberg BS. Moderate elevation of body iron level and increased risk of cancer occurrence and death. Int J Cancer. 1994; 56(3): 364-9[PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

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