Zahedan Journal of Research in Medical Sciences

Published by: Kowsar

Comparing the Effect of Pentoxifylline Administration on Mast Cells Maturing Process in a Diabetic and Normoglycemic Rat Wound Healing

Saeid Babaei 1 , Mohammad Bayat 2 , Bahram Kazemi 3 , Nariman Mossafa 4 , Ali Ghanbari 5 , * , Mojgan Bandepoor 3 , Fateme Fadaee 2 and Mohammad Jalili 2
Authors Information
1 Department of Anatomy, Arak University of Medical Sciences, Arak, Iran
2 Department of Biology and Anatomy, Shahid Beheshty University of Medical Sciences, Tehran, Iran
3 Cell and Molecular Biology Research Center, Shahid Beheshty University of Medical Sciences, Tehran, Iran
4 Department of Immunology, Shahid Beheshty University of Medical Sciences, Tehran, Iran
5 Fertility and Infertility Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran
Article information
  • Zahedan Journal of Research in Medical Sciences: July 20, 2013, 16 (12); e23396
  • Published Online: December 15, 2014
  • Article Type: Research Article
  • Received: May 10, 2012
  • Accepted: June 5, 2012

To Cite: Babaei S, Bayat M, Kazemi B, Mossafa N, Ghanbari A, et al. Comparing the Effect of Pentoxifylline Administration on Mast Cells Maturing Process in a Diabetic and Normoglycemic Rat Wound Healing, Zahedan J Res Med Sci. 2013 ; 16(12):e23396.

Abstract
Copyright © 2014 Zahedan University of Medical Sciences. All rights reserved.This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
Introduction
Materials and Methods
Results
Discussion
Acknowledgements
Footnotes
References
  • 1. Brem H, Tomic-Canic M. Cellular and molecular basis of wound healing in diabetes. J Clin Invest. 2007; 117(5): 1219-22[DOI][PubMed]
  • 2. Sebag J, Tang M, Brown S, Sadun AA, Charles MA. Effects of pentoxifylline on choroidal blood flow in nonproliferative diabetic retinopathy. Angiology. 1994; 45(6): 429-33[PubMed]
  • 3. Hebda PA, Collins MA, Tharp MD. Mast cell and myofibroblast in wound healing. Dermatol Clin. 1993; 11(4): 685-96[PubMed]
  • 4. Khoshvaghti A, Zibamanzarmofrad M, Bayat M. Effect of low-level treatment with an 80-Hz pulsed infrared diode laser on mast-cell numbers and degranulation in a rat model of third-degree burn. Photomed Laser Surg. 2011; 29(9): 597-604[DOI][PubMed]
  • 5. Zhou QG, Zheng FL, Hou FF. Inhibition of tubulointerstitial fibrosis by pentoxifylline is associated with improvement of vascular endothelial growth factor expression. Acta Pharmacol Sin. 2009; 30(1): 98-106[DOI][PubMed]
  • 6. de Campos T, Deree J, Martins JO, Loomis WH, Shenvi E, Putnam JG, et al. Pentoxifylline attenuates pulmonary inflammation and neutrophil activation in experimental acute pancreatitis. Pancreas. 2008; 37(1): 42-9[DOI][PubMed]
  • 7. Vukovic M, Lapcevic M. [The role of pentoxifylline in nitrogen conversion in patients suffering from diabetic phlegmona of the foot]. Srp Arh Celok Lek. 2006; 134 Suppl 2: 119-21[PubMed]
  • 8. Marques LJ, Zheng L, Poulakis N, Guzman J, Costabel U. Pentoxifylline inhibits TNF-alpha production from human alveolar macrophages. Am J Respir Crit Care Med. 1999; 159(2): 508-11[DOI][PubMed]
  • 9. Aviado DM, Porter JM. Pentoxifylline: a new drug for the treatment of intermittent claudication. Mechanism of action, pharmacokinetics, clinical efficacy and adverse effects. Pharmacotherapy. 1984; 4(6): 297-307[PubMed]
  • 10. Sullivan GW, Carper HT, Novick WJ, Mandell GL. Inhibition of the inflammatory action of interleukin-1 and tumor necrosis factor (alpha) on neutrophil function by pentoxifylline. Infect Immun. 1988; 56(7): 1722-9[PubMed]
  • 11. Lin HY, Yeh CT. Controlled release of pentoxifylline from porous chitosan-pectin scaffolds. Drug Deliv. 2010; 17(5): 313-21[DOI][PubMed]
  • 12. Yessenow RS, Maves MD. The effects of pentoxifylline on random skin flap survival. Arch Otolaryngol Head Neck Surg. 1989; 115(2): 179-81[PubMed]
  • 13. Wang W, Lin S, Xiao Y, Huang Y, Tan Y, Cai L, et al. Acceleration of diabetic wound healing with chitosan-crosslinked collagen sponge containing recombinant human acidic fibroblast growth factor in healing-impaired STZ diabetic rats. Life Sci. 2008; 82(3-4): 190-204[DOI][PubMed]
  • 14. Karasoy A KI, Turan T. The effect of pentoxifylline on the healing of full- Thickness skin defects of diabetic and normal rats. Eur J Plast Surg. 2002; 25(5): 253-7[DOI]
  • 15. Amadeu T, Braune A, Mandarim-de-Lacerda C, Porto LC, Desmouliere A, Costa A. Vascularization pattern in hypertrophic scars and keloids: a stereological analysis. Pathol Res Pract. 2003; 199(7): 469-73[DOI][PubMed]
  • 16. Andriessen MP, van Bergen BH, Spruijt KI, Go IH, Schalkwijk J, van de Kerkhof PC. Epidermal proliferation is not impaired in chronic venous ulcers. Acta Derm Venereol. 1995; 75(6): 459-62[PubMed]
  • 17. Beukelman CJ, van den Berg AJ, Hoekstra MJ, Uhl R, Reimer K, Mueller S. Anti-inflammatory properties of a liposomal hydrogel with povidone-iodine (Repithel) for wound healing in vitro. Burns. 2008; 34(6): 845-55[DOI][PubMed]
  • 18. Falanga V. Wound healing and its impairment in the diabetic foot. Lancet. 2005; 366(9498): 1736-43[DOI][PubMed]
  • 19. LeRoy EC, Trojanowska M, Smith EA. The pathogenesis of scleroderma (systemic sclerosis, SSc). Clin Exp Rheumatol. 1991; 9(2): 173-7[PubMed]
  • 20. Trautmann A, Feuerstein B, Ernst N, Brocker EB, Klein CE. Heterotypic cell-cell adhesion of human mast cells to fibroblasts. Arch Dermatol Res. 1997; 289(4): 194-203[PubMed]
  • 21. Trautmann A, Toksoy A, Engelhardt E, Brocker EB, Gillitzer R. Mast cell involvement in normal human skin wound healing: expression of monocyte chemoattractant protein-1 is correlated with recruitment of mast cells which synthesize interleukin-4 in vivo. J Pathol. 2000; 190(1): 100-6[DOI][PubMed]
  • 22. Bayat M, Chelcheraghi F, Piryaei A, Rakhshan M, Mohseniefar Z, Rezaie F, et al. The effect of 30-day pretreatment with pentoxifylline on the survival of a random skin flap in the rat: an ultrastructural and biomechanical evaluation. Med Sci Monit. 2006; 12(6)-7[PubMed]
  • 23. LeRoy EC, Trojanowska M, Smith EA. The pathogenesis of scleroderma (systemic sclerosis, SSc). Clin Exp Rheumatol. 1991; 9(2): 173-7[PubMed]
  • 24. Kofford MW, Schwartz LB, Schechter NM, Yager DR, Diegelmann RF, Graham MF. Cleavage of type I procollagen by human mast cell chymase initiates collagen fibril formation and generates a unique carboxyl-terminal propeptide. J Biol Chem. 1997; 272(11): 7127-31[PubMed]
  • 25. Kameyoshi Y, Morita E, Tanaka T, Hiragun T, Yamamoto S. Interleukin-1 alpha enhances mast cell growth by a fibroblast-dependent mechanism. Arch Dermatol Res. 2000; 292(5): 240-7[PubMed]
  • 26. Conti P, Boucher W, Letourneau R, Feliciani C, Reale M, Barbacane RC, et al. Monocyte chemotactic protein-1 provokes mast cell aggregation and [3H]5HT release. Immunology. 1995; 86(3): 434-40[PubMed]
  • 27. Lin SL, Chen YM, Chien CT, Chiang WC, Tsai CC, Tsai TJ. Pentoxifylline attenuated the renal disease progression in rats with remnant kidney. J Am Soc Nephrol. 2002; 13(12): 2916-29[PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments