Zahedan Journal of Research in Medical Sciences

Published by: Kowsar

Effects of Cardiac Resynchronization Therapy on Mitral Regurgitation in Heart Failure Patients

Jalal Kheirkhah 1 , Vahid Toulabi 1 , Hassan Moladoust 1 , * , Mohammad Assadian-Rad 1 , Hamid Reza Bonakdar 1 , Anoosh Barzigar 1 , Fardin Mirbolouk 1 , Bijan Shad 1 and Vahid Nikseresht 1
Authors Information
1 Cardiovascular Research Center, Guilan University of Medical Sciences, Rasht, Iran
Article information
  • Zahedan Journal of Research in Medical Sciences: January 28, 2015, 17 (1); e1919
  • Published Online: October 5, 2013
  • Article Type: Research Article
  • Received: May 15, 2013
  • Accepted: September 3, 2013

To Cite: Kheirkhah J, Toulabi V, Moladoust H, Assadian-Rad M, Reza Bonakdar H, et al. Effects of Cardiac Resynchronization Therapy on Mitral Regurgitation in Heart Failure Patients, Zahedan J Res Med Sci. 2015 ; 17(1):e1919.

Copyright © 2015, Zahedan University of Medical Sciences. All rights reserved.This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
Materials and Methods
  • 1. Roger VL, Go AS, Lloyd-Jones DM, Adams RJ, Berry JD, Brown TM, et al. Heart disease and stroke statistics--2011 update: a report from the American Heart Association. Circulation. 2011; 123(4)[DOI][PubMed]
  • 2. Karami M, Khalili D, Eshrati B. Estimating the proportion of diabetes to the attributable burden of cardiovascular diseases in iran. Iran J Public Health. 2012; 41(8): 50-5[PubMed]
  • 3. Linde C, Leclercq C, Rex S, Garrigue S, Lavergne T, Cazeau S, et al. Long-term benefits of biventricular pacing in congestive heart failure: results from the MUltisite STimulation in cardiomyopathy (MUSTIC) study. J Am Coll Cardiol. 2002; 40(1): 111-8[PubMed]
  • 4. Abraham WT, Fisher WG, Smith AL, Delurgio DB, Leon AR, Loh E, et al. Cardiac resynchronization in chronic heart failure. N Engl J Med. 2002; 346(24): 1845-53[DOI][PubMed]
  • 5. Farwell D, Patel NR, Hall A, Ralph S, Sulke AN. How many people with heart failure are appropriate for biventricular resynchronization? Eur Heart J. 2000; 21(15): 1246-50[DOI][PubMed]
  • 6. Aaronson KD, Schwartz JS, Chen TM, Wong KL, Goin JE, Mancini DM. Development and prospective validation of a clinical index to predict survival in ambulatory patients referred for cardiac transplant evaluation. Circulation. 1997; 95(12): 2660-7[PubMed]
  • 7. Acosta H, Viafara LM, Izquierdo D, Adams D, Pothula VR, Wallner H. Reduction of mitral regurgitation by biventricular pacing with intraventriuclar timing optimization in patients without a standard indication: A potential new indication for Cardiac Resynchronization Therapy. J Innov Cardiac Rhythm Manag. 2012; 3: 784-90
  • 8. St John Sutton MG, Plappert T, Abraham WT, Smith AL, DeLurgio DB, Leon AR, et al. Effect of cardiac resynchronization therapy on left ventricular size and function in chronic heart failure. Circulation. 2003; 107(15): 1985-90[DOI][PubMed]
  • 9. Horwich T, Foster E, De Marco T, Tseng Z, Saxon L. Effects of resynchronization therapy on cardiac function in pacemaker patients "upgraded" to biventricular devices. J Cardiovasc Electrophysiol. 2004; 15(11): 1284-9[DOI][PubMed]
  • 10. Cleland JG, Daubert JC, Erdmann E, Freemantle N, Gras D, Kappenberger L, et al. The effect of cardiac resynchronization on morbidity and mortality in heart failure. N Engl J Med. 2005; 352(15): 1539-49[DOI][PubMed]
  • 11. Hassaniani Z, Keirkhah J, Moladoust H, Bonakdar HR, Assadian Rad M, Barzigar A, et al. Evaluation of left ventricular systolic function after cardiac resynchronization therapy in heart failure patients. Zahedan Journal of Research in Medical Sciences. 2013; 15(9): 18-22
  • 12. Eskesen K, Kanagalingam S, Abraham TP. Mitral regurgitation in cardiac resynchronization: solving another piece of the puzzle. Circ Cardiovasc Imaging. 2009; 2(6): 427-8[DOI][PubMed]
  • 13. Ypenburg C, Lancellotti P, Tops LF, Bleeker GB, Holman ER, Pierard LA, et al. Acute effects of initiation and withdrawal of cardiac resynchronization therapy on papillary muscle dyssynchrony and mitral regurgitation. J Am Coll Cardiol. 2007; 50(21): 2071-7[DOI][PubMed]
  • 14. Lancellotti P, Melon P, Sakalihasan N, Waleffe A, Dubois C, Bertholet M, et al. Effect of cardiac resynchronization therapy on functional mitral regurgitation in heart failure. Am J Cardiol. 2004; 94(11): 1462-5[DOI][PubMed]
  • 15. Kanzaki H, Bazaz R, Schwartzman D, Dohi K, Sade LE, Gorcsan J3. A mechanism for immediate reduction in mitral regurgitation after cardiac resynchronization therapy: insights from mechanical activation strain mapping. J Am Coll Cardiol. 2004; 44(8): 1619-25[DOI][PubMed]
  • 16. Disney PJ, Ashby DT, Young GD. Biventricular pacing for severe mitral regurgitation following atrioventricular nodal ablation. Pacing Clin Elecrophys. 2003; 26(2pt1): 643-4[DOI]
  • 17. Breithardt OA, Sinha AM, Franke A, Hanrath P, Stellbrink C. [Echocardiography in cardiac resynchronization therapy: identification of suitable patients, follow-up and therapy optimization]. Herz. 2003; 28(7): 615-27[DOI][PubMed]
  • 18. Irwin JM, Glover MU, Barold SS. Treatment of pacemaker induced severe mitral regurgitation with biventricular pacing in two patients with a normal left ventricular ejection fraction. Pacing Clin Electrophysiol. 2003; 26(12): 2333-5[PubMed]
  • 19. Auricchio A, Stellbrink C, Sack S, Block M, Vogt J, Bakker P, et al. Long-term clinical effect of hemodynamically optimized cardiac resynchronization therapy in patients with heart failure and ventricular conduction delay. J Am Coll Cardiol. 2002; 39(12): 2026-33[PubMed]
  • 20. Bristow MR, Saxon LA, Boehmer J, Krueger S, Kass DA, De Marco T, et al. Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. N Engl J Med. 2004; 350(21): 2140-50[DOI][PubMed]
  • 21. Young JB, Abraham WT, Smith AL, Leon AR, Lieberman R, Wilkoff B, et al. Combined cardiac resynchronization and implantable cardioversion defibrillation in advanced chronic heart failure: the MIRACLE ICD Trial. JAMA. 2003; 289(20): 2685-94[DOI][PubMed]
  • 22. Gras D, Leclercq C, Tang AS, Bucknall C, Luttikhuis HO, Kirstein-Pedersen A. Cardiac resynchronization therapy in advanced heart failure the multicenter InSync clinical study. Eur J Heart Fail. 2002; 4(3): 311-20[PubMed]
  • 23. Etienne Y, Mansourati J, Touiza A, Gilard M, Bertault-Valls V, Guillo P, et al. Evaluation of left ventricular function and mitral regurgitation during left ventricular-based pacing in patients with heart failure. Eur J Heart Fail. 2001; 3(4): 441-7[PubMed]
  • 24. Breithardt OA, Sinha AM, Schwammenthal E, Bidaoui N, Markus KU, Franke A, et al. Acute effects of cardiac resynchronization therapy on functional mitral regurgitation in advanced systolic heart failure. J Am Coll Cardiol. 2003; 41(5): 765-70[PubMed]
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