Zahedan Journal of Research in Medical Sciences

Published by: Kowsar

Effects of Ten Weeks of Aerobic Interval Training and Four Weeks Detraining on Plasma Adiponectin Level in Male Student Non-Athletes

Karim Dehghani 1 , * and Mehdi Mogharnasi 2
Authors Information
1 Department of Exercise Physiology, University of Sistan and Baluchestan, Zahedan, IR Iran
2 Department of Physical Education, University of Sistan and Baluchestan, Zahedan, IR Iran
Article information
  • Zahedan Journal of Research in Medical Sciences: October 28, 2015, 17 (10); e2085
  • Published Online: October 25, 2015
  • Article Type: Research Article
  • Received: June 14, 2014
  • Accepted: July 2, 2014
  • DOI: 10.17795/zjrms-2085

To Cite: Dehghani K, Mogharnasi M. Effects of Ten Weeks of Aerobic Interval Training and Four Weeks Detraining on Plasma Adiponectin Level in Male Student Non-Athletes, Zahedan J Res Med Sci. 2015 ; 17(10):e2085. doi: 10.17795/zjrms-2085.

Copyright © 2015, Zahedan University of Medical Sciences.This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Ronti T, Lupattelli G, Mannarino E. The endocrine function of adipose tissue: an update. Clin Endocrinol (Oxf). 2006; 64(4): 355-65[DOI][PubMed]
  • 2. Nemet D, Wang P, Funahashi T, Matsuzawa Y, Tanaka S, Engelman L, et al. Adipocytokines, body composition, and fitness in children. Pediatr Res. 2003; 53(1): 148-52[DOI][PubMed]
  • 3. Goldstein BJ, Scalia RG, Ma XL. Protective vascular and myocardial effects of adiponectin. Nat Clin Pract Cardiovasc Med. 2009; 6(1): 27-35[DOI][PubMed]
  • 4. Ouchi N, Kihara S, Arita Y, Nishida M, Matsuyama A, Okamoto Y, et al. Adipocyte-derived plasma protein, adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation. 2001; 103(8): 1057-63[PubMed]
  • 5. Monzillo LU, Hamdy O, Horton ES, Ledbury S, Mullooly C, Jarema C, et al. Effect of lifestyle modification on adipokine levels in obese subjects with insulin resistance. Obes Res. 2003; 11(9): 1048-54[DOI][PubMed]
  • 6. Rubin DA, McMurray RG, Harrell JS, Hackney AC, Thorpe DE, Haqq AM. The association between insulin resistance and cytokines in adolescents: the role of weight status and exercise. Metabolism. 2008; 57(5): 683-90[DOI][PubMed]
  • 7. Giannopoulou I, Fernhall B, Carhart R, Weinstock RS, Baynard T, Figueroa A, et al. Effects of diet and/or exercise on the adipocytokine and inflammatory cytokine levels of postmenopausal women with type 2 diabetes. Metabolism. 2005; 54(7): 866-75[DOI][PubMed]
  • 8. Lim S, Choi SH, Jeong IK, Kim JH, Moon MK, Park KS, et al. Insulin-sensitizing effects of exercise on adiponectin and retinol-binding protein-4 concentrations in young and middle-aged women. J Clin Endocrinol Metab. 2008; 93(6): 2263-8[DOI][PubMed]
  • 9. Kraemer RR, Castracane VD. Exercise and humoral mediators of peripheral energy balance: ghrelin and adiponectin. Exp Biol Med (Maywood). 2007; 232(2): 184-94[PubMed]
  • 10. Polak J, Klimcakova E, Moro C, Viguerie N, Berlan M, Hejnova J, et al. Effect of aerobic training on plasma levels and subcutaneous abdominal adipose tissue gene expression of adiponectin, leptin, interleukin 6, and tumor necrosis factor alpha in obese women. Metabolism. 2006; 55(10): 1375-81[DOI][PubMed]
  • 11. Kobayashi J, Murase Y, Asano A, Nohara A, Kawashiri MA, Inazu A, et al. Effect of walking with a pedometer on serum lipid and adiponectin levels in Japanese middle-aged men. J Atheroscler Thromb. 2006; 13(4): 197-201[PubMed]
  • 12. Fu Y, Luo N, Klein RL, Garvey WT. Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation. J Lipid Res. 2005; 46(7): 1369-79[DOI][PubMed]
  • 13. Dabidi-Roushan VA, Sadeghpour B, Jahanian Z. The effect of exhaustive running with different intensities on adiponectin concentration in active females.[in Persian] Persian. Sport Biosci. 2010; 1(3): 21-39
  • 14. Mohebbi H, Moghadasi M, Rahmaninia F. Effect of 12 weeks high intensity aerobic training and a week detraining on plasma adiponectin, insulin resistance and central and peripheral fat volume in obese middle age men.[in Persian] Persian Olympic. 2010; 3(18): 33-46
  • 15. Zeng Q, Isobe K, Fu L, Ohkoshi N, Ohmori H, Takekoshi K, et al. Effects of exercise on adiponectin and adiponectin receptor levels in rats. Life Sci. 2007; 80(5): 454-9[DOI][PubMed]
  • 16. Ferguson MA, White LJ, McCoy S, Kim HW, Petty T, Wilsey J. Plasma adiponectin response to acute exercise in healthy subjects. Eur J Appl Physiol. 2004; 91(2-3): 324-9[DOI][PubMed]
  • 17. Punyadeera C, Zorenc AH, Koopman R, McAinch AJ, Smit E, Manders R, et al. The effects of exercise and adipose tissue lipolysis on plasma adiponectin concentration and adiponectin receptor expression in human skeletal muscle. Eur J Endocrinol. 2005; 152(3): 427-36[DOI][PubMed]
  • 18. Yatagai T, Nishida Y, Nagasaka S, Nakamura T, Tokuyama K, Shindo M, et al. Relationship between exercise training-induced increase in insulin sensitivity and adiponectinemia in healthy men. Endocr J. 2003; 50(2): 233-8[PubMed]
  • 19. Hara T, Fujiwara H, Nakao H, Mimura T, Yoshikawa T, Fujimoto S. Body composition is related to increase in plasma adiponectin levels rather than training in young obese men. Eur J Appl Physiol. 2005; 94(5-6): 520-6[DOI][PubMed]
  • 20. Fatouros IG, Tournis S, Leontsini D, Jamurtas AZ, Sxina M, Thomakos P, et al. Leptin and adiponectin responses in overweight inactive elderly following resistance training and detraining are intensity related. J Clin Endocrinol Metab. 2005; 90(11): 5970-7[DOI][PubMed]
  • 21. Jones TE, Basilio JL, Brophy PM, McCammon MR, Hickner RC. Long-term exercise training in overweight adolescents improves plasma peptide YY and resistin. Obesity (Silver Spring). 2009; 17(6): 1189-95[DOI][PubMed]
  • 22. Adamopoulos S, Parissis J, Kroupis C, Georgiadis M, Karatzas D, Karavolias G, et al. Physical training reduces peripheral markers of inflammation in patients with chronic heart failure. Eur Heart J. 2001; 22(9): 791-7[DOI][PubMed]
  • 23. Jurimae J, Purge P, Jurimae T. Adiponectin and stress hormone responses to maximal sculling after volume-extended training season in elite rowers. Metabolism. 2006; 55(1): 13-9[DOI][PubMed]
  • 24. Ring-Dimitriou S, Paulweber B, von Duvillard SP, Stadlmann M, LeMura LM, Lang J, et al. The effect of physical activity and physical fitness on plasma adiponectin in adults with predisposition to metabolic syndrome. Eur J Appl Physiol. 2006; 98(5): 472-81[DOI][PubMed]
  • 25. Ryan AS, Berman DM, Nicklas BJ, Sinha M, Gingerich RL, Meneilly GS, et al. Plasma adiponectin and leptin levels, body composition, and glucose utilization in adult women with wide ranges of age and obesity. Diabetes Care. 2003; 26(8): 2383-8[PubMed]
  • 26. Guebre-Egziabher F, Bernhard J, Funahashi T, Hadj-Aissa A, Fouque D. Adiponectin in chronic kidney disease is related more to metabolic disturbances than to decline in renal function. Nephrol Dial Transplant. 2005; 20(1): 129-34[DOI][PubMed]
  • 27. Altinova AE, Toruner FB, Akturk M, Bukan N, Cakir N, Ayvaz G, et al. Adiponectin levels and cardiovascular risk factors in hypothyroidism and hyperthyroidism. Clin Endocrinol (Oxf). 2006; 65(4): 530-5[DOI][PubMed]
  • 28. Smith J, Al-Amri M, Sniderman A, Cianflone K. Leptin and adiponectin in relation to body fat percentage, waist to hip ratio and the apoB/apoA1 ratio in Asian Indian and Caucasian men and women. Nutr Metab (Lond). 2006; 3: 18[DOI][PubMed]
  • 29. Mohebi HGE. Effect of intensity training on plasma adiponectin concentration in male rat.[in Persian] Persian. Olympic. 2009; 16(4): 71-8
  • 30. Goodarzi MO, Dumesic DA, Chazenbalk G, Azziz R. Polycystic ovary syndrome: etiology, pathogenesis and diagnosis. Nat Rev Endocrinol. 2011; 7(4): 219-31[DOI][PubMed]
  • 31. Boudou P, Sobngwi E, Mauvais-Jarvis F, Vexiau P, Gautier JF. Absence of exercise-induced variations in adiponectin levels despite decreased abdominal adiposity and improved insulin sensitivity in type 2 diabetic men. Eur J Endocrinol. 2003; 149(5): 421-4[PubMed]
  • 32. Stefan N, Vozarova B, Funahashi T, Matsuzawa Y, Weyer C, Lindsay RS, et al. Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans. Diabetes. 2002; 51(6): 1884-8[PubMed]
  • 33. Huang H, Iida KT, Sone H, Ajisaka R. The regulation of adiponectin receptors expression by acute exercise in mice. Exp Clin Endocrinol Diabetes. 2007; 115(7): 417-22[DOI][PubMed]
  • 34. Hamedinia MR, Haghighi AH. The effect of aerobic training on serum adiponectin and insulin resistance index in overweight men. [in Persian]. Persian Olympic. 2006; 13(4): 41-50
  • 35. Khedri G, Mogharnasi M. Interaction effect of 8-week aerobic exercise and omega-3 fatty acid supplementation on plasma adiponectin concentration. Zahedan J Res Med Sci. 2013; 15(3): 36-41
  • 36. Ahmadizad S, Haghighi AH, Hamedinia MR. Effects of resistance versus endurance training on serum adiponectin and insulin resistance index. Eur J Endocrinol. 2007; 157(5): 625-31[DOI][PubMed]
  • 37. Coker RH, Williams RH, Kortebein PM, Sullivan DH, Evans WJ. Influence of exercise intensity on abdominal fat and adiponectin in elderly adults. Metab Syndr Relat Disord. 2009; 7(4): 363-8[DOI][PubMed]
  • 38. Ziccardi P, Nappo F, Giugliano G, Esposito K, Marfella R, Cioffi M, et al. Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year. Circulation. 2002; 105(7): 804-9[PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .
Readers' Comments