Zahedan Journal of Research in Medical Sciences

Published by: Kowsar

Risk of Squamous Cell Carcinoma of Esophagus and its Relation to Consumption of Antioxidant Vitamins in Kurdistan Province

Seyedeh Sameneh Hassani 1 , Bahare Hajizadeh 2 , Majid Hajifaraji 3 , Anahita Hoshyarrad 2 , Roya Aghazadeh 1 and Bahram Rashidkhani 4 , *
Authors Information
1 Departmemt of Nutrition, International Branch, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
2 National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
3 Departmemt of Nutrition, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
4 Department of Community Nutrition, Faculty of Nutrition and Food Sciences, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
Article information
  • Zahedan Journal of Research in Medical Sciences: October 28, 2015, 17 (10); e2190
  • Published Online: October 25, 2015
  • Article Type: Research Article
  • Received: July 16, 2012
  • Accepted: August 16, 2012
  • DOI: 10.17795/zjrms-2190

To Cite: Hassani S S, Hajizadeh B, Hajifaraji M, Hoshyarrad A, Aghazadeh R, et al. Risk of Squamous Cell Carcinoma of Esophagus and its Relation to Consumption of Antioxidant Vitamins in Kurdistan Province, Zahedan J Res Med Sci. 2015 ; 17(10):e2190. doi: 10.17795/zjrms-2190.

Copyright © 2015, Zahedan University of Medical Sciences.This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Mehrabi Y, Yavari P, Abadi A. A study of cancer patterns among inpatients of public hospitals in Iran. Asian Pac J Cancer Prev. 2004; 5(4): 387-92[PubMed]
  • 2. World Health Organization . All cancers (excluding non-melanoma skin cancer) estimated incidence, mortality, and prevalence worldwide in 2012. 2012;
  • 3. Ghavamzadeh A, Moussavi A, Jahani M, Rastegarpanah M, Iravani M. Esophageal cancer in Iran. Semin Oncol. 2001; 28(2): 153-7[PubMed]
  • 4. Siassi F, Pouransari Z, Ghadirian P. Nutrient intake and esophageal cancer in the Caspian littoral of Iran: a case-control study. Cancer Detect Prev. 2000; 24(3): 295-303[PubMed]
  • 5. Hormozdiari H, Day NE, Aramesh B, Mahboubi E. Dietary factors and esophageal cancer in the Caspian Littoral of Iran. Cancer Res. 1975; 35(11 Pt. 2): 3493-8[PubMed]
  • 6. Siassi F, Ghadirian P. Riboflavin deficiency and esophageal cancer: a case control-household study in the Caspian Littoral of Iran. Cancer Detect Prev. 2005; 29(5): 464-9[DOI][PubMed]
  • 7. Lopez-Garcia E, Schulze MB, Fung TT, Meigs JB, Rifai N, Manson JE, et al. Major dietary patterns are related to plasma concentrations of markers of inflammation and endothelial dysfunction. Am J Clin Nutr. 2004; 80(4): 1029-35[PubMed]
  • 8. Mirmiran P, Esfahani FH, Mehrabi Y, Hedayati M, Azizi F. Reliability and relative validity of an FFQ for nutrients in the Tehran lipid and glucose study. Public Health Nutr. 2010; 13(5): 654-62[DOI][PubMed]
  • 9. Esfahani FH, Asghari G, Mirmiran P, Azizi F. Reproducibility and relative validity of food group intake in a food frequency questionnaire developed for the Tehran Lipid and Glucose Study. J Epidemiol. 2010; 20(2): 150-8[PubMed]
  • 10. Taylor PR, Li B, Dawsey SM, Li JY, Yang CS, Guo W, et al. Prevention of esophageal cancer: the nutrition intervention trials in Linxian, China. Linxian Nutrition Intervention Trials Study Group. Cancer Res. 1994; 54(7 Suppl): 2029s-31s[PubMed]
  • 11. Rashidkhani B, Hajizadeh-Armaki B, Houshiar-Rad A, Moasheri M. Dietary patterns and risk of squamous-cell carcinoma of esophagus in Kurdistan province, Iran [in Persian] . Iran J Nutr Sci Food Technol. 2008; 3(3): 11-21
  • 12. Franceschi S, Bidoli E, Negri E, Zambon P, Talamini R, Ruol A, et al. Role of macronutrients, vitamins and minerals in the aetiology of squamous-cell carcinoma of the oesophagus. Int J Cancer. 2000; 86(5): 626-31[PubMed]
  • 13. Carman S, Kamangar F, Freedman ND, Wright ME, Dawsey SM, Dixon LB, et al. Vitamin E intake and risk of esophageal and gastric cancers in the NIH-AARP Diet and Health Study. Int J Cancer. 2009; 125(1): 165-70[DOI][PubMed]
  • 14. Abnet CC, Chen W, Dawsey SM, Wei WQ, Roth MJ, Liu B, et al. Serum 25(OH)-vitamin D concentration and risk of esophageal squamous dysplasia. Cancer Epidemiol Biomarkers Prev. 2007; 16(9): 1889-93[DOI][PubMed]
  • 15. Bollschweiler E, Wolfgarten E, Nowroth T, Rosendahl U, Monig SP, Holscher AH. Vitamin intake and risk of subtypes of esophageal cancer in Germany. J Cancer Res Clin Oncol. 2002; 128(10): 575-80[DOI][PubMed]
  • 16. Wolfgarten E, Rosendahl U, Nowroth T, Leers J, Metzger R, Holscher AH, et al. Coincidence of nutritional habits and esophageal cancer in Germany. Onkologie. 2001; 24(6): 546-51[PubMed]
  • 17. Chen X, Mikhail SS, Ding YW, Yang G, Bondoc F, Yang CS. Effects of vitamin E and selenium supplementation on esophageal adenocarcinogenesis in a surgical model with rats. Carcinogenesis. 2000; 21(8): 1531-6[PubMed]
  • 18. Rodler I, Zajkas G. Hungarian cancer mortality and food availability data in the last four decades of the 20th century. Ann Nutr Metab. 2002; 46(2): 49-56[PubMed]
  • 19. Mettlin C, Graham S, Priore R, Marshall J, Swanson M. Diet and cancer of the esophagus. Nutr Cancer. 1981; 2(3): 143-7[DOI][PubMed]
  • 20. Fontham ET, Su LJ. Preventive nutrition. 2005;
  • 21. Hoefert S, Bloch T, Wierich W, Eufinger H. [Rare entity of a macroscopically visible tumor cone of squamous cell carcinoma in the greater veins of the head and neck]. Mund Kiefer Gesichtschir. 2006; 10(1): 46-9[DOI][PubMed]
  • 22. Schorah CJ, Sobala GM, Sanderson M, Collis N, Primrose JN. Gastric juice ascorbic acid: effects of disease and implications for gastric carcinogenesis. Am J Clin Nutr. 1991; 53(1 Suppl): 287S-93S[PubMed]
  • 23. Levine M, Rumsey SC, Daruwala R, Park JB, Wang Y. Criteria and recommendations for vitamin C intake. JAMA. 1999; 281(15): 1415-23[PubMed]
  • 24. Ramos AC, Araujo MR, Lopes LR, Andreollo NA. Role of the vitamin C in diethylnitrosamine-induced esophageal cancer in Wistar rats. Acta Cir Bras. 2009; 24(3): 183-8[PubMed]
  • 25. Grdisa M, Kralj M, Eckert-Maksic M, Maksic ZB, Pavelic K. 6-Amino-6-deoxyascorbic acid induces apoptosis in human tumor cells. J Cancer Res Clin Oncol. 1995; 121(2): 98-102[PubMed]
  • 26. Fraga CG, Motchnik PA, Shigenaga MK, Helbock HJ, Jacob RA, Ames BN. Ascorbic acid protects against endogenous oxidative DNA damage in human sperm. Proc Natl Acad Sci U S A. 1991; 88(24): 11003-6[PubMed]
  • 27. Wang GQ, Dawsey SM, Li JY, Taylor PR, Li B, Blot WJ, et al. Effects of vitamin/mineral supplementation on the prevalence of histological dysplasia and early cancer of the esophagus and stomach: results from the General Population Trial in Linxian, China. Cancer Epidemiol Biomarkers Prev. 1994; 3(2): 161-6[PubMed]
  • 28. Gao YT, McLaughlin JK, Gridley G, Blot WJ, Ji BT, Dai Q, et al. Risk factors for esophageal cancer in Shanghai, China. II. Role of diet and nutrients. Int J Cancer. 1994; 58(2): 197-202[PubMed]
  • 29. Tzonou A, Lipworth L, Garidou A, Signorello LB, Lagiou P, Hsieh C, et al. Diet and risk of esophageal cancer by histologic type in a low-risk population. Int J Cancer. 1996; 68(3): 300-4[DOI][PubMed]
  • 30. Mayne ST, Risch HA, Dubrow R, Chow WH, Gammon MD, Vaughan TL, et al. Nutrient intake and risk of subtypes of esophageal and gastric cancer. Cancer Epidemiol Biomarkers Prev. 2001; 10(10): 1055-62[PubMed]
  • 31. Ziegler RG, Morris LE, Blot WJ, Pottern LM, Hoover R, Fraumeni JJ. Esophageal cancer among black men in Washington, D.C. II. Role of nutrition. J Natl Cancer Inst. 1981; 67(6): 1199-206[PubMed]
  • 32. Launoy G, Faivre J, Pienkowski P, Milan C, Gignoux M, Pottier D. Changing pattern of oesophageal cancer incidence in France. Int J Epidemiol. 1994; 23(2): 246-51[PubMed]
  • 33. Tavani A, Negri E, Franceschi S, La Vecchia C. Risk factors for esophageal cancer in lifelong nonsmokers. Cancer Epidemiol Biomarkers Prev. 1994; 3(5): 387-92[PubMed]
  • 34. Hu J, Nyren O, Wolk A, Bergstrom R, Yuen J, Adami HO, et al. Risk factors for oesophageal cancer in northeast China. Int J Cancer. 1994; 57(1): 38-46[PubMed]
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