Zahedan Journal of Research in Medical Sciences

Published by: Kowsar

Studying the Proteomic Pattern of Cancerous Tissue in Patients With Breast Cancer and Its' Comparing With Healthy Breast

Firooz Behboodi 1 , Mostafa Rezaei Tavirani 2 , * , Shahrokh Yousefzadeh 3 , Haniyeh Bashizadeh-Fakhar 2 , Behrang Ashoorizadeh 4 , Roya Faraji 5 , Ehsan Kazem-Nejad 6 and Hakimeh Zali 2
Authors Information
1 Department of Surgery, Guilan University of Medical Sciences, Rasht, IR Iran
2 Proteomics Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
3 Department of Neurosurgery, Guilan Road Truma Research Center, Guilan University of Medical Sciences, Rasht, IR Iran
4 Department of Surgery, Sabzevar University of Medical Sciences, Sabzevar, IR Iran
5 Department of Gynecology, Guilan University of Medical Sciences, Rasht, IR Iran
6 Department of Biostatistics, Guilan Road Truma Research Center, Guilan University of Medical Sciences, Rasht, IR Iran
Article information
  • Zahedan Journal of Research in Medical Sciences: November 28, 2015, 17 (11); e2197
  • Published Online: November 1, 2015
  • Article Type: Research Article
  • Received: March 17, 2014
  • Accepted: April 22, 2014
  • DOI: 10.17795/zjrms-2197

To Cite: Behboodi F, Rezaei Tavirani M, Yousefzadeh S, Bashizadeh-Fakhar H, Ashoorizadeh B, et al. Studying the Proteomic Pattern of Cancerous Tissue in Patients With Breast Cancer and Its' Comparing With Healthy Breast, Zahedan J Res Med Sci. 2015 ; 17(11):e2197. doi: 10.17795/zjrms-2197.

Copyright © 2015, Zahedan University of Medical Sciences.This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Chu KC, Tarone RE, Kessler LG, Ries LA, Hankey BF, Miller BA, et al. Recent trends in U.S. breast cancer incidence, survival, and mortality rates. J Natl Cancer Inst. 1996; 88(21): 1571-9[PubMed]
  • 2. Behboudi F, Ashoorizadeh B, Kazemnejad E, Bashizadeh-Fakhar H. Gail model to determine the risk of breast cancer. J Guilan Univ Med Sci. 2013; 22(88): 7-11
  • 3. Harirchi I, Ebrahimi M, Zamani N, Jarvandi S, Montazeri A. Breast cancer in Iran. Public Health. 2000; 114(2): 143-5[DOI]
  • 4. Harirchi I, Karbakhsh M, Kashefi A, Momtahen AJ. Breast cancer in Iran: results of a multi-center study. Asian Pac J Cancer Prev. 2004; 5(1): 24-7[PubMed]
  • 5. Bashar Z, Murray N, Cutress R. Indentification of 27 putative breast cancer proteomic biomarkers by SELDI-TOFMS. Eur J Surg Oncol. 2009; 35(11): 1230-3
  • 6. Banks E, Reeves G, Beral V, Bull D, Crossley B, Simmonds M, et al. Influence of personal characteristics of individual women on sensitivity and specificity of mammography in the Million Women Study: cohort study. BMJ. 2004; 329(7464): 477[DOI][PubMed]
  • 7. Wulfkuhle JD, Liotta LA, Petricoin EF. Proteomic applications for the early detection of cancer. Nat Rev Cancer. 2003; 3(4): 267-75[DOI][PubMed]
  • 8. Wang LY, Chakraborty A, Comaniciu D. Molecular diagnosis and biomarker identification on SELDI proteomics data by ADTBoost method. Conf Proc IEEE Eng Med Biol Soc. 2005; 5: 4771-4[DOI][PubMed]
  • 9. Kolch W, Mischak H, Pitt AR. The molecular make-up of a tumour: proteomics in cancer research. Clin Sci (Lond). 2005; 108(5): 369-83[DOI][PubMed]
  • 10. Beranova-Giorgianni S. Proteome analysis by two-dimensional gel electrophoresis and mass spectrometry: strengths and limitations. TrAC Trends Analytic Chem. 2003; 22(5): 273-81[DOI]
  • 11. Patterson SD, Aebersold RH. Proteomics: the first decade and beyond. Nat Genet. 2003; 33 Suppl: 311-23[DOI][PubMed]
  • 12. Reif DM, White BC, Moore JH. Integrated analysis of genetic, genomic and proteomic data. Expert Rev Proteomics. 2004; 1(1): 67-75[DOI][PubMed]
  • 13. Nouri T, Zahmaatkesh T, Mallae T, Akbari P. Breast cancer risk assessment models by using Gail model. J Breast Dis. 2008; 2(3): 54-8
  • 14. Jemal A, Siegel R, Ward E, Murray T, Xu J, Smigal C, et al. Cancer statistics, 2006. CA Cancer J Clin. 2006; 56(2): 106-30[PubMed]
  • 15. Huang HL, Hsing HW, Lai TC, Chen YW, Lee TR, Chan HT, et al. Trypsin-induced proteome alteration during cell subculture in mammalian cells. J Biomed Sci. 2010; 17: 36[DOI][PubMed]
  • 16. Timms JF, Cramer R. Difference gel electrophoresis. Proteomics. 2008; 8(23-24): 4886-97[DOI]
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