Zahedan Journal of Research in Medical Sciences

Published by: Kowsar

The Effect of Gold Nano Particles Compared to Dioxide Titanium Nano Particles on Vital Factors of Isolated Candida albicans in Patients with Oral Candidiasis in Vitro

Ladan Rahimzadeh Torabi 1 , * and Monir Doudi 2
Authors Information
1 MSc of Microbiology, Falavarjan Branch, Islamic Azad University, Isfahan, Iran
2 Department of Microbiology, Falavarjan Branch, Islamic Azad University, Isfahan, Iran
Article information
  • Zahedan Journal of Research in Medical Sciences: December 2016, 18 (12); e5666
  • Published Online: December 14, 2016
  • Article Type: Research Article
  • Received: February 9, 2016
  • Revised: April 11, 2016
  • Accepted: December 6, 2016
  • DOI: 10.17795/zjrms-5666

To Cite: Rahimzadeh Torabi L, Doudi M. The Effect of Gold Nano Particles Compared to Dioxide Titanium Nano Particles on Vital Factors of Isolated Candida albicans in Patients with Oral Candidiasis in Vitro, Zahedan J Res Med Sci. 2016 ; 18(12):e5666. doi: 10.17795/zjrms-5666.

Copyright © 2016, Zahedan University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Hoepelman IM, Dupont B. Oral candidiasis: the clinical challenge of resistance and management. Int J Antimicrob Agents. 1996; 6(3): 155-9[DOI][PubMed]
  • 2. Kwon-Chung KJ, Bennett JE. Candidiasis. 1992; : 280-336
  • 3. Hay RJ. The management of superficial candidiasis. J Am Acad Dermatol. 1999; 40(6 Pt 2): 35-42[DOI][PubMed]
  • 4. Naeini A, Khosarvi AR, Chitsaz M, Shokri H, Kamlnejad M. Anti-Candida albicans activity of some Iranian plants used in traditional medicine. Mycol Med. 2009; 19(3): 168-72[DOI]
  • 5. Johann S, Silva DL, Martins CVB, Zani CL, Pizzolatti MG, Resende MA. Inhibitory effect of extracts from Brazilian medicinal plants on the adhesion of Candida albicans to buccal epithelial cells. World J Microbiol Biotechnol. 2008; 24: 2459-64[DOI]
  • 6. Noumi E, Snoussi M, Hajlaoui H, Valentin E, Bakhrouf A. Antifungal properties of Salvadora persica and Juglans regia L. extracts against oral Candida strains. Eur J Clin Microbiol Infect Dis. 2010; 29(1): 81-8[DOI][PubMed]
  • 7. Kuriyama T, Williams DW, Bagg J, Coulter WA, Ready D, Lewis MA. In vitro susceptibility of oral Candida to seven antifungal agents. Oral Microbiol Immunol. 2005; 20(6): 349-53[DOI][PubMed]
  • 8. Lynch DP. Oral candidiasis. History, classification, and clinical presentation. Oral Surg Oral Med Oral Pathol. 1994; 78(2): 189-93[DOI][PubMed]
  • 9. Nirmala Grace A, Pandian K. Antibacterial efficacy of aminoglycosidic antibiotics protected gold nanoparticles-a brief study. Colloids and Surfaces A: Physicochem. Eng Aspects. 2007; 1(3): 63-70[DOI]
  • 10. Panyala NR, Pena-Mendez EM, Havel J. Gold and nano gold in medicine: overview, toxicology and perspectives. J Appl Biomed. 2009; 7(1): 75-91
  • 11. Zawrah MF, Abd El-Moez SI. Antimicrobial activities of gold nanoparticles against major Food borne pathogens. Life Science J. 2011; 8(4): 37-44
  • 12. Jebali A, Hajjar FH, Pourdanesh F, Hekmatimoghaddam S, Kazemi B, Masoudi A, et al. Silver and gold nanostructures: antifungal property of different shapes of these nanostructures on Candida species. Med Mycol. 2014; 52(1): 65-72[DOI][PubMed]
  • 13. Chwalibog A, Sawosz E, Hotowy A, Szeliga J, Mitura S, Mitura K, et al. Visualization of interaction between inorganic nanoparticles and bacteria or fungi. Int J Nanomedicine. 2010; 5: 1085-94[DOI][PubMed]
  • 14. Munro C. Candida albicans cell wall mediated virulence. 2010; : 69-95
  • 15. Connor EE, Mwamuka J, Gole A, Murphy CJ, Wyatt MD. Gold nanoparticles are taken up by human cells but do not cause acute cytotoxicity. Small. 2005; 1(3): 325-7[DOI][PubMed]
  • 16. Zheng Y, Sanche L. Gold nanoparticles enhance DNA damage induced by anti-cancer drugs and radiation. Radiat Res. 2009; 172(1): 114-9[DOI][PubMed]
  • 17. Wani IA, Ahmad T, Manzoor N. Size and shape dependant antifungal activity of gold nanoparticles: a case study of Candida. Colloids Surf B Biointerfaces. 2013; 101: 162-70[DOI][PubMed]
  • 18. Ninane J. A multicentre study of fluconazole versus oral polyenes in the prevention of fungal infection in children with hematological or oncological malignancies. Multicentre Study Group. Eur J Clin Microbiol Infect Dis. 1994; 13(4): 330-7[DOI][PubMed]
  • 19. Battin TJ, Kammer FV, Weilhartner A, Ottofuelling S, Hofmann T. Nanostructured TiO2: transport behavior and effects on aquatic microbial communities under environmental conditions. Environ Sci Technol. 2009; 43(21): 8098-104[DOI][PubMed]
  • 20. Seven O, Dindar B, Aydemir S, Metin D, Ozinel M, Icli S. Solar photocatalytic disinfection of a group of bacteria and fungi aqueous suspensions with TiO2, ZnO and Sahara desert dust. J Photochem Photobiol A: Chem. 2004; 165(1-3): 103-7[DOI]
  • 21. Mizugai H, Isogai E, Hirose K, Chiba I. Effect of denture wearing on occurrence of candida Species in the Oral Cavity. J Appl Res. 2007; 7(3): 250-4
  • 22. Jafari Nadooshan AA, Fllah Tafti A, Ghafoor Zadeh M, Mirzaii F. The frequency of candida and staphylococcus colonization in the oral cavity of the elderly [in Persian]. Med Laborat J. 2008; 2(1): 26-31
  • 23. Odman PA. The effectiveness of an enzyme-containing denture cleanser. Quintessence Int. 1992; 23(3): 187-90[PubMed]
  • 24. Enyashin AN, Seifert G. Structure, stability and electronic properties of TiO2 nanostructures. Physica Status Solidi. 2005; 242(7): 1361-70[DOI]
  • 25. Sellvaraj V, Grace AN, Alagar M, Hamerton I. Antimicrobial And Anticancer Efficiancy Of Antineoplastic Agent Capped Gold Nanoparticles. J Biomed Nanotechnol. 2010; 6(2): 129-37[DOI]
  • 26. Hoshi N, Mori H, Taguchi H, Taniguchi M, Aoki H, Sawada T, et al. Management of oral candidiasis in denture wearers. J Prosthodont Res. 2011; 55(1): 48-52[DOI][PubMed]
  • 27. Emami E, de Grandmont P, Rompre PH, Barbeau J, Pan S, Feine JS. Favoring trauma as an etiological factor in denture stomatitis. J Dent Res. 2008; 87(5): 440-4[DOI][PubMed]
  • 28. Daniluk T, Tokajuk G, Stokowska W, Fiedoruk K, Sciepuk M, Zaremba ML, et al. Occurrence rate of oral Candida albicans in denture wearer patients. Adv Med Sci. 2006; 51 Suppl 1: 77-80[PubMed]
  • 29. Epstein JB. Antifungal therapy in oropharyngeal mycotic infections. Oral Surg Oral Med Oral Pathol. 1990; 69(1): 32-41[DOI][PubMed]
  • 30. Zegarelli DJ. Fungal infections of the oral cavity. Otolaryngol Clin North Am. 1993; 26(6): 1069-89[PubMed]
  • 31. Khan MS, Malik A, Ahmad I. Anti-candidal activity of essential oils alone and in combination with amphotericin B or fluconazole against multi-drug resistant isolates of Candida albicans. Med Mycol. 2012; 50(1): 33-42[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments