Zahedan Journal of Research in Medical Sciences

Published by: Kowsar

The Loop-Mediated Isothermal Amplification Method Instead of PCR in Detection Goals

Peyman Avakh Majelan 1 , Mehdi Fatahi Bafghi 2 , Javad Alizadeh 3 , Nasrin Pourramezan 1 and Davoud Afshar 4 , *
Authors Information
1 Department of Pathobiology, Faculty of Public Health, Tehran University of Medical ‎Sciences, Tehran, ‎IR Iran
2 Department of Microbiology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, IR Iran
3 Department of Human Anatomy and Cell Science, Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada
4 Department of Microbiology, Zanjan University of Medical Sciences, Zanjan, IR Iran
Article information
  • Zahedan Journal of Research in Medical Sciences: June 30, 2016, 18 (6); e7354
  • Published Online: June 15, 2016
  • Article Type: Letter
  • Received: February 3, 2015
  • Accepted: May 25, 2015
  • DOI: 10.17795/zjrms-7354

To Cite: Avakh Majelan P, Fatahi Bafghi M, Alizadeh J, Pourramezan N, Afshar D. The Loop-Mediated Isothermal Amplification Method Instead of PCR in Detection Goals, Zahedan J Res Med Sci. 2016 ; 18(6):e7354. doi: 10.17795/zjrms-7354.

Copyright © 2016, Zahedan University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
  • 1. Notomi T, Okayama H, Masubuchi H, Yonekawa T, Watanabe K, Amino N, et al. Loop-mediated isothermal amplification of DNA. Nucleic Acids Res. 2000; 28(12)[PubMed]
  • 2. Yoshida A, Nagashima S, Ansai T, Tachibana M, Kato H, Watari H, et al. Loop-mediated isothermal amplification method for rapid detection of the periodontopathic bacteria Porphyromonas gingivalis, Tannerella forsythia, and Treponema denticola. J Clin Microbiol. 2005; 43(5): 2418-24[DOI][PubMed]
  • 3. Mori Y, Nagamine K, Tomita N, Notomi T. Detection of loop-mediated isothermal amplification reaction by turbidity derived from magnesium pyrophosphate formation. Biochem Biophys Res Commun. 2001; 289(1): 150-4[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

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