Zahedan Journal of Research in Medical Sciences

Published by: Kowsar

The Antioxidant Effects of Artemisia deserti Ethanolic Extract and Diazinon on Male Rat Kidney

Ali Noori 1 , * , Leila Amjad 1 and Fereshteh Yazdani 2
Authors Information
1 Department of Biology, Falavarjan Branch, Islamic Azad University, Isfahan, IR Iran
2 Young Researchers and Elite Club, Falavarjan Branch, Islamic Azad University, Isfahan, Iran
Article information
  • Zahedan Journal of Research in Medical Sciences: June 30, 2016, 18 (6); e7366
  • Published Online: June 15, 2016
  • Article Type: Research Article
  • Received: February 2, 2015
  • Accepted: September 13, 2015
  • DOI: 10.17795/zjrms-7366

To Cite: Noori A, Amjad L, Yazdani F. The Antioxidant Effects of Artemisia deserti Ethanolic Extract and Diazinon on Male Rat Kidney, Zahedan J Res Med Sci. 2016 ; 18(6):e7366. doi: 10.17795/zjrms-7366.

Copyright © 2016, Zahedan University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Materials and Methods
4. Results
5. Discussion
  • 1. Bodhisattwa M, Nagori BP, Rambir S, Kumar P, Upadhyay N. Recent trends in herbal drugs: A review. Int J Drug Res Tech. 2011; 1(1): 17-25
  • 2. Karakoca K, Ozusaglam MA, Cakmak YS, Erkul SK. Antioxidative, antimicrobial and cytotoxic properties of Isatis floribunda Boiss. ex Bornm. extracts. EXCLI J. 2013; 12: 150-67[PubMed]
  • 3. Garcia S, McArthur ED, Pellicer J, Sanderson SC, Valles J, Garnatje T. A molecular phylogenetic approach to western North America endemic Artemisia and allies (Asteraceae): untangling the sagebrushes. Am J Bot. 2011; 98(4): 638-53[DOI][PubMed]
  • 4. Yazdani F, Noori A, Amjad L. Effect of Artemisia deserti flowering taps extract on liver in male rats. Int J Agric Crop Sci. 2013; 5(13): 1432
  • 5. Kazemi M, Shafizadeh S, Larijani K. Comparison of essential oils composition of stem, leaf and flower from artemisia deserti kracsh. J Appl Chem Res. 2011; 18: 29-34
  • 6. Noori A, Amjad L, Yazdani F. The effects of Artemisia deserti ethanolic extract on pathology and function of rat kidney. Avicenna J Phytomed. 2014; 4(6): 371-6[PubMed]
  • 7. Molan AL, Faraj AM, Mahdy AS. Antioxidant activity and phenolic content of some medicinal plants traditionally used in Northern Iraq. Phytopharmaco. 2012; 2: 224-33
  • 8. Moujerloo M. Variations of lipid peroxidation and superoxide dismutase activity due to haemodialysis in gorgan. J Clin Diagn Res. 2010; 4(4): 2763-7
  • 9. Ugusman A, Zakaria Z, Chua K, Nordin NMM, Mahdy ZA. Flavanoids of Piper sarmentosum and its cytoprotective effects against oxidative stress. EXCLI J. 2012; 11: 705-14
  • 10. Razavi M, Hosseinzadeh H, Abnous K, Motamedshariaty VS, Imenshahidi M. Crocin restores hypotensive effect of subchronic administration of diazinon in rats. Iran J Basic Med Sci. 2013; 16(1): 64-72[PubMed]
  • 11. Ene-ojo A, Ene-ojo AS, Chinedu EA, Yakasai FM. Toxic Effects of Sub-Chronic Administration of Chloroform Extract of Artemisia maciverae Linn on the Kidney of Swiss Albino Rats. Int J Biochem Res Rev. 2013; 3(2): 119-28[DOI]
  • 12. Esterbauer H, Cheeseman KH. Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Methods Enzymol. 1990; 186: 407-21[PubMed]
  • 13. Benzie IF, Strain JJ. Ferric reducing/antioxidant power assay: direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration. Methods Enzymol. 1999; 299: 15-27[PubMed]
  • 14. Jayasimha GB, Danamma B, Nizamuddin SB, Dayananda KS, Chikka SBK. Hypo glycemic activity of a methanol extract of Artemisia absinthium leaves in experimental rats. Int J Adv Pharm Res. 2011; 2(7): 307-12
  • 15. Sunmonu TO, Afolayan AJ. Evaluation of Antidiabetic Activity and Associated Toxicity of Artemisia afra Aqueous Extract in Wistar Rats. Evid Based Complement Alternat Med. 2013; 2013: 929074[DOI][PubMed]
  • 16. Al-Soqeer A. Antioxidant Activity and Biological Evaluation of Hot-water Extract of Artemisia monosperma and Capparis spinosa Against Lead Contamination. Res J Bot. 2011; 6(1): 11-20[DOI]
  • 17. Temraz A, El-Tantawy WH. Characterization of antioxidant activity of extract from Artemisia vulgaris. Pak J Pharm Sci. 2008; 21(4): 321-6[PubMed]
  • 18. Amirkabirian N, Teimouri F, Esmaily H, Mohammadirad A, Aliahmadi A, Abdollahi M. Protection by pentoxifylline of diazinon-induced toxic stress in rat liver and muscle. Toxicol Mech Methods. 2007; 17(4): 215-21[DOI][PubMed]
  • 19. Jia X, Zhao C, Chen Y. The in vitro and in vivo antioxidant activities of various extracts from Artemisisa selengensis Turcz. Recent Advances in Clinical Medicine. 2010;
  • 20. Amat N, Upur H, Blazekovic B. In vivo hepatoprotective activity of the aqueous extract of Artemisia absinthium L. against chemically and immunologically induced liver injuries in mice. J Ethnopharmacol. 2010; 131(2): 478-84[DOI][PubMed]
  • 21. Sarhan OMM, Al-Sahhaf ZY. Histological and biochemical effects of diazinon on liver and kidney of rabbits. Life Sci. J. 2011; 8(4): 1183-9
  • 22. Hassan SA, El-Shawaf IM, El-Ghazaly A, El-Azab SM. Ozone Administration Ameliorates Different Chemically Induced Hepato-Renal Chronic Toxicity in Rats: a Histopathological Study. Forensic Med Clin Toxicol. 2007; 15(2): 57-72
  • 23. El-Shenawy NS, Al-Eisa RA, El-Salmy F, Salah O. Prophylactic effect of vitamin E against hepatotoxicity, nephrotoxicity, haematological indices and histopathology induced by diazinon insecticide in mice. Curr Zool. 2009; 55(3): 219-26
  • 24. Shokrzade M, Abbasi A, Shadborestan A, Omidi M. Pathology examination of liver and kidney in diazinon exposed rat and role of L-carnitine [in Persian]. JMUMS. 2013; 22(2): 140-4
  • 25. Salih EMA. Toxic effect of dimethoate and diazinon on the biochemical and hematological parameters in male rabbits. Jordan J Biol Sci. 2010; 3(2): 77-82
  • 26. Adam SE, Al-Qarawi AA, Elhag EA. Effects of various levels of dietary Artemisia abyssinica leaves on rats. Lab Anim. 2000; 34(3): 307-12[PubMed]
  • 27. Chaturvedi D. Sesquiterpene lactones: structural diversity and their biological activities, In-Opportunity, Challanges and Scope of Natural Products in Medicinal Chemistry. Research Signpost. 2011; 1(2): 313-4
  • 28. Ferreira JF, Luthria DL, Sasaki T, Heyerick A. Flavonoids from Artemisia annua L. as antioxidants and their potential synergism with artemisinin against malaria and cancer. Molecules. 2010; 15(5): 3135-70[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments