Zahedan Journal of Research in Medical Sciences

Published by: Kowsar

Protective Effects of Aloe Vera on Superovulated Oocytes and Folliculogenesis in Diabetic Mice

Mahsa Afrough 1 , * , Naeem Erfani Majd 1 and Hossein Najafzadeh 2
Authors Information
1 Department of Histology, Faculty of Veterinary Medicine, Shahid Chamran University, Ahvaz, IR Iran
2 Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Shahid Chamran University, Ahvaz, IR Iran
Article information
  • Zahedan Journal of Research in Medical Sciences: August 2016, 18 (8); e7939
  • Published Online: July 31, 2016
  • Article Type: Short Communication
  • Received: May 5, 2015
  • Accepted: May 5, 2015
  • DOI: 10.17795/zjrms-7939

To Cite: Afrough M, Erfani Majd N, Najafzadeh H. Protective Effects of Aloe Vera on Superovulated Oocytes and Folliculogenesis in Diabetic Mice, Zahedan J Res Med Sci. 2016 ; 18(8):e7939. doi: 10.17795/zjrms-7939.

Abstract
Copyright © 2016, Zahedan University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
Acknowledgements
Footnotes
References
  • 1. Doblado M, Moley KH. Glucose metabolism in pregnancy and embryogenesis. Curr Opin Endocrinol Diabetes Obes. 2007; 14(6): 488-93[DOI][PubMed]
  • 2. Hosseinifar S, Erfanimajd N, Morovvati H, Najafzadeh H. Aloe vera gel protects ovarian structure in diabetic rat. Am-Eurasian J Toxico Sci. 2011; 3(3): 197-203
  • 3. Chang AS, Dale AN, Moley KH. Maternal diabetes adversely affects preovulatory oocyte maturation, development, and granulosa cell apoptosis. Endocrinology. 2005; 146(5): 2445-53[DOI][PubMed]
  • 4. Colton SA, Pieper GM, Downs SM. Altered meiotic regulation in oocytes from diabetic mice. Biol Reprod. 2002; 67(1): 220-31[PubMed]
  • 5. Kim NN, Stankovic M, Cushman TT, Goldstein I, Munarriz R, Traish AM. Streptozotocin-induced diabetes in the rat is associated with changes in vaginal hemodynamics, morphology and biochemical markers. BMC Physiol. 2006; 6: 4[DOI][PubMed]
  • 6. Rajasekaran S, Sivagnanam K, Subramanian S. Antioxidant effect of Aloe vera gel extract in streptozotocin-induced diabetes in rats. Pharmacol Rep. 2005; 57(1): 90-6[PubMed]
  • 7. Okyar A, Can A, Akev N, Baktir G, Sutlupinar N. Effect of Aloe vera leaves on blood glucose level in type I and type II diabetic rat models. Phytother Res. 2001; 15(2): 157-61[PubMed]
  • 8. Hamman JH. Composition and applications of Aloe vera leaf gel. Molecules. 2008; 13(8): 1599-616[PubMed]
  • 9. Perez YY, Jimenez-Ferrer E, Zamilpa A, Hernandez-Valencia M, Alarcon-Aguilar FJ, Tortoriello J, et al. Effect of a polyphenol-rich extract from Aloe vera gel on experimentally induced insulin resistance in mice. Am J Chin Med. 2007; 35(6): 1037-46[DOI][PubMed]
  • 10. Sivagnanam S, Subramanian KS. Antioxidant effect of Aloe vera gel extract in streptozotocin-induced diabetes in rats. Pharmacol Report. 2005; 57(1): 90-6
  • 11. Diamond MP, Moley KH, Pellicer A, Vaughn WK, DeCherney AH. Effects of streptozotocin- and alloxan-induced diabetes mellitus on mouse follicular and early embryo development. J Reprod Fertil. 1989; 86(1): 1-10[PubMed]
  • 12. Powers RW, Chambers C, Larsen WJ. Diabetes-mediated decreases in ovarian superoxide dismutase activity are related to blood-follicle barrier and ovulation defects. Endocrinology. 1996; 137(7): 3101-10[DOI][PubMed]
  • 13. Wang Q, Ratchford AM, Chi MM, Schoeller E, Frolova A, Schedl T, et al. Maternal diabetes causes mitochondrial dysfunction and meiotic defects in murine oocytes. Mol Endocrinol. 2009; 23(10): 1603-12[DOI][PubMed]
  • 14. Kosif R, Aktas RG. Investigation of the effects of Aloe barbadensis on rat ovaries: a preliminary study. J Med Food. 2009; 12(6): 1393-7[DOI][PubMed]
  • 15. Khaksar Z, Jelodar G, Hematian H, Poorahmadi M. Ovarian Histomorphometry at Puberty in Rat Offspring from Diabetic Mothers. World J Zoology. 2013; 8(1): 24-9
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