Zahedan Journal of Research in Medical Sciences

Published by: Kowsar

A Gene Expression Profile of Alzheimer’s Disease Using Microarray Technology

Marie Barati 1 and Mansour Ebrahim 2 , *
Authors Information
1 University of Applied Science and Technology Centre of Nehbandan, Nehbandan, IR Iran
2 Department of Biology, School of Basic Sciences, Qom University, Qom, IR Iran
Article information
  • Zahedan Journal of Research in Medical Sciences: August 2016, 18 (8); e7950
  • Published Online: August 1, 2016
  • Article Type: Research Article
  • Received: June 29, 2015
  • Accepted: November 12, 2015
  • DOI: 10.17795/zjrms-7950

To Cite: Barati M, Ebrahim M. A Gene Expression Profile of Alzheimer’s Disease Using Microarray Technology, Zahedan J Res Med Sci. 2016 ; 18(8):e7950. doi: 10.17795/zjrms-7950.

Copyright © 2016, Zahedan University of Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Methods
4. Results
5. Discussion
  • 1. Waldemar G, Dubois B, Emre M, Georges J, McKeith IG, Rossor M, et al. Recommendations for the diagnosis and management of Alzheimer's disease and other disorders associated with dementia: EFNS guideline. Eur J Neurol. 2007; 14(1): 1-26[DOI][PubMed]
  • 2. Tabert MH, Liu X, Doty RL, Serby M, Zamora D, Pelton GH, et al. A 10-item smell identification scale related to risk for Alzheimer's disease. Ann Neurol. 2005; 58(1): 155-60[DOI][PubMed]
  • 3. Sung HC, Chang AM. Use of preferred music to decrease agitated behaviours in older people with dementia: a review of the literature. J Clin Nurs. 2005; 14(9): 1133-40[DOI][PubMed]
  • 4. Forbes DA. Strategies for managing behavioural symptomatology associated with dementia of the Alzheimer type: a systematic overview. Can J Nurs Res. 1998; 30(2): 67-86[PubMed]
  • 5. Rolland Y, Andrieu S, Cantet C, Morley JE, Thomas D, Nourhashemi F, et al. Wandering behavior and Alzheimer disease. The REAL.FR prospective study. Alzheimer Dis Assoc Disord. 2007; 21(1): 31-8[DOI][PubMed]
  • 6. Shimabukuro J, Awata S, Matsuoka H. Behavioral and psychological symptoms of dementia characteristic of mild Alzheimer patients. Psychiatry Clin Neurosci. 2005; 59(3): 274-9[DOI][PubMed]
  • 7. Teri L. Behavior and caregiver burden: behavioral problems in patients with Alzheimer disease and its association with caregiver distress. Alzheimer Dis Assoc Disord. 1997; 11 Suppl 4: 35-8[PubMed]
  • 8. Contributors . DNA microarray. 2014;
  • 9. Chow N, Cox C, Callahan LM, Weimer JM, Guo L, Coleman PD. Expression profiles of multiple genes in single neurons of Alzheimer's disease. Proc Natl Acad Sci U S A. 1998; 95(16): 9620-5[PubMed]
  • 10. Pongrac J, Middleton FA, Lewis DA, Levitt P, Mirnics K. Gene expression profiling with DNA microarrays: advancing our understanding of psychiatric disorders. Neurochem Res. 2002; 27(10): 1049-63[PubMed]
  • 11. Marcotte ER, Srivastava LK, Quirion R. cDNA microarray and proteomic approaches in the study of brain diseases: focus on schizophrenia and Alzheimer's disease. Pharmacol Ther. 2003; 100(1): 63-74[PubMed]
  • 12. Goodman G, Limbird L, Hardman J. The pharmacological Basis of therapeutics. 2001;
  • 13. Assistive technology for promoting physical and mental exercise to delay progression of cognitive degeneration in patients with dementia. 2007 Ieee Biomedical Circuits and Systems Conference. : 235-8
  • 14. Rezaee FE, Motamed N, Habibi M. Micro-array technology. 1390;
  • 15. Adomas A, Heller G, Olson A, Osborne J, Karlsson M, Nahalkova J, et al. Comparative analysis of transcript abundance in Pinus sylvestris after challenge with a saprotrophic, pathogenic or mutualistic fungus. Tree Physiol. 2008; 28(6): 885-97[PubMed]
  • 16. Loring JF, Wen X, Lee JM, Seilhamer J, Somogyi R. A gene expression profile of Alzheimer's disease. DNA Cell Biol. 2001; 20(11): 683-95[DOI][PubMed]
  • 17. Arisi I, D'Onofrio M, Brandi R, Felsani A, Capsoni S, Drovandi G, et al. Gene expression biomarkers in the brain of a mouse model for Alzheimer's disease: mining of microarray data by logic classification and feature selection. J Alzheimers Dis. 2011; 24(4): 721-38[DOI][PubMed]
  • 18. Ricciarelli R, d'Abramo C, Massone S, Marinari U, Pronzato M, Tabaton M. Microarray analysis in Alzheimer's disease and normal aging. IUBMB Life. 2004; 56(6): 349-54[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .
Readers' Comments