The Comparison of Eucalyptus Aqueous Extract and Insulin on Blood Sugar and Liver Enzymes in Diabetic Male Rats

AUTHORS

Ahmadreza Shahraki 1 , Mohammad Reza Shahraki 2 , *

AUTHORS INFORMATION

1 General Physician, Zahedan University of Medical Sciences, Zahedan, Iran

2 Department of Physiology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran

How to Cite: Shahraki A, Shahraki M R . The Comparison of Eucalyptus Aqueous Extract and Insulin on Blood Sugar and Liver Enzymes in Diabetic Male Rats, Zahedan J Res Med Sci. 2013 ; 15(6):e92955.

ARTICLE INFORMATION

Zahedan Journal of Research in Medical Sciences: 15 (6); e92955
Published Online: October 29, 2012
Article Type: Research Article
Received: November 13, 2011
Accepted: January 18, 2012

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Abstract

Background : Since eucalyptus is a traditional plant which has been consumed as antidiabetic in herbal medicines, the aim of this survey was to compare the effect of eucalyptus aqueous extract and insulin on serum blood sugar and liver enzymes in streptozotocin (STZ) diabetic male rats.
Material & Methods : The experiment was performed on four groups of rats: sham control (A), diabetic control (B), diabetic (C) which received insulin and diabetic group (D) which consumed Eucalyptus aqueous extract in drinking water for 4 weeks (n=8). Sham control and B group did not receive any agents. At the end, animals were deep anesthetized by diethyl ether, sacrificed and blood samples were collected. Blood sugar, serum lipids and liver enzymes were measured by ordinary methods. Obtained data were analyzed using ANOVA and Tukey tests. Results were expressed as mean±SD. Statistical difference of p<0.05 was recognized significant.
Results : Results showed that blood sugar in group C significantly decreased compared with that of group B but ALT, AST and ALP activity value significantly increased compared with those of other groups.
Conclusion : These results indicated that Eucalyptus aqueous extract caused decreased blood sugar but increased liver enzymes activity in STZ diabetic male rats.

Keywords

Eucalyptus Lipoprotein Male rat Blood glucose Liver enzymes

© 2013, Zahedan Journal of Research in Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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