The Effects of Three Sessions of Running on a Negative Slope on Serum Levels of Liver Enzymes in Adult Male Rats

AUTHORS

Mohsen Rezaei 1 , * , eskandar rahimi 1 , somayeh bordbar 1 , Sahar Namdar 1

AUTHORS INFORMATION

1 Department of Exercise Physiology, Fars Sciences and Research Branch, Islamic Azad University, Shiraz, Iran

ARTICLE INFORMATION

Zahedan Journal of Research in Medical Sciences: 15 (5); e92989
Published Online: November 18, 2012
Article Type: Short Communication
Received: August 22, 2011
Accepted: May 06, 2012

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Abstract

Background: The purpose of this study was to investigate the effects of three sessions of running on a negative slope (eccentric contraction) on changes of the serum levels of aspartate aminotransferase (AST) and alanin aminotransferaze (ALT) in adult male rats.
Materials and Methods: 20 adult male rats were divided randomly into two equal groups (exercise and control). Levels of AST and ALT in both groups were measured in a fasting state, 24 hours before and 24 hours after the last session of training.
Results: Exercise increased the levels of serum AST and ALT enzymes, significantly (p<0.05).
Conclusion: Eccentric exercise, without allowing enough time for returning to the pre-exercise state, leads to the damage of some body organs such as the liver.

Keywords

Eccentric contraction Aspartate aminotransferase Alanine aminotransferase Muscle Injury

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