The Comparison of Pain Relief between Postoperative Wound Infiltration with Bupivacaine 0.5% Combined with Epinephrine after Elective Cesarean Section


vida modarres nejad 1 , * , batool Motamedi 2 , Mazyar Nafisy 3


1 Department of Obstetrics and Gynecology, Kerman University of Medical Sciences, Kerman, Iran

2 Department of Midwifery, Kerman University of Medical Sciences, Kerman, Iran

3 General Physician, Kerman University of Medical Sciences, Kerman, Iran


Zahedan Journal of Research in Medical Sciences: 15 (4); e92997
Published Online: November 15, 2012
Article Type: Research Article
Received: June 04, 2011
Accepted: August 06, 2011




Background : So many methods have been developed and tested to control post-surgical pain. In this study, the effect of bupivacaine-H medicine (along with epinephrine) on the post-surgical pain reduction in cesarean mothers was examined.
Materials and Method s: In a double blind randomized clinical trial study conducted in Kerman, 70 pregnant women who were eligible for elective cesarean section participated in the study as randomized into two case and control groups. In all the patients, cesarean section incision lengths were equal and bupivacaine was injected after infant delivery. In the control group, physiological serum was used as placebo instead of medicine. Pain severity was compared between two groups using Visual Analogue Scale (VAS) on 6, 12, 24 and 48 hours after operation. The results were analyzed applying SPSS-11 software and using Mann-Whitney U and Wilcoxon tests.
Results : Mean age of the patients was 25.36 years with standard aviation of 2.48 years and the age range of 18-28 years. A previous cesarean with relative frequency of 38.5 percent was the main cause of cesarean section in such patients. In the case group, pain severity before 24 hours was less than that in the control group. After 24 hours of the operation, the pain severity in both case and control groups were similar.
Conclusion : In general, bupivacaine injection into the cesarean incision area will cause to reduce the pain after cesarean section in the mothers and considering its minor complications, such medicine may be used as an effective pain control method in women.


Pain relief Bupivacaine post-operative Cesarean Section

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