The Influence of Nine-Week Intensive Aerobic Exercises, Calcium and Vitamin D Supplementation on the Metabolic Response of Bone Formation Biomarkers
Zahedan Journal of Research in Medical Sciences: February 28, 2013, 15 (2); e93098
October 28, 2012
Article Type: Research Article
April 23, 2011
June 08, 2011
J. The Influence of Nine-Week Intensive Aerobic Exercises, Calcium and Vitamin D Supplementation on the Metabolic Response of Bone Formation Biomarkers,
Zahedan J Res Med Sci.
The purpose of the study is to analyze the impact of 9-week intensive aerobic exercises and the calcium and vitamin D supplement intake on the indicators which show bone formation in young women. Background : 44 non-athletic women in their thirties (27.18±3.65) were studied randomly in four groups: 1) Exercise, 2) Calcium and vitamin D supplement, 3) Exercise and supplement, and 4) control. The subjects exercised three sessions a week for 9 weeks, each session lasted 30-45 minutes. The blood and urinary samples were collected from the experimental and control groups while they fasted either before or after exercise program. The concentration of alkaline phosphates and procollagen I, C terminal (PICP) had been measured using DGKC and HPLC techniques, respectively. The collected data had been combined with the statistical t-tests and were analyzed by ANCOVA (p<0.05). Materials and Methods : Significant increasing of ALP and PICP was observed in exercise group (p=0.001) and exercise + supplement group (p=0.001). In supplement group, alkaline phosphate and procollagen type 1, C-terminal show a significant decrease (p=0.001), while the difference was not significant in the control group. Results : Generally, the research results show that the intensive aerobic exercise and adequate intake of calcium and vitamin D affect positively the bone mass development during youth and they reduce fracture risk however, such claim needs further investigations.
Calcium and vitamin D; supplement; Procollagen type 1; C-terminal propeptide; Alkaline phosphatase; Intensive aerobic exercises
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