Evaluation Chemical Composition of Unstimulated Saliva, in Patients with Type I Diabetes Mellitus

AUTHORS

Masoomeh Shirzaii 1 , * , Fathemeh Heidari 2

1 Department of Oral and Maxillofacial Surgeon, Faculty of Dentistry, Zahedan University of Medical Sciences, Zahedan, Iran

2 Department of Pathology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran

How to Cite: Shirzaii M, Heidari F. Evaluation Chemical Composition of Unstimulated Saliva, in Patients with Type I Diabetes Mellitus, Zahedan J Res Med Sci. 2013 ; 15(1):e93134.

ARTICLE INFORMATION

Zahedan Journal of Research in Medical Sciences: 15 (1); e93134
Published Online: April 09, 2012
Article Type: Research Article
Received: August 21, 2011
Accepted: October 13, 2011

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Abstract

Background : Diabetes will result in change in qualitative and quantitative function of saliva. The purpose of the study was to determine the chemical composition (combination) of unstimulated saliva in patients with type I diabetes mellitus.
Materials and Methods : In this case-control study, unstimulated saliva of 25 patients with type I controlled diabetes (20-30 years) and 25 healthy person who matched with the case group in respect of age and gender was gathered and analyzed in order to evaluate the chemical composition of saliva. The data was analyzed using SPSS-18 and independent t-test.
Results : Salivary Ca2+ concentration in diabetic patients was equivalent to 9.2±2.3 mg/dl and in healthy individuals was 9.4±0.7 mg/dl Sodium level (Na+) in diabetics was equal to 1.3±11.8 mg/dl and in healthy individuals was 9.9±2.5 mg/dl Potassium level (K+) in diabetics was equal to 19.5±6.3 mg/dl and in healthy individuals was 15.8±4.4 mg/dl Urea level in diabetics was equal to 19±3.8 mg/dl and in healthy individuals 9.7±1.4 mg/dl and Phosphorus level (P+) in diabetics was equivalent to 12.7±4.6 mg/dl and in healthy individuals was 11±4.8 mg/dl. Salivary K+, Urea, and Na+ concentration in both groups was significantly different (p=0.05).
Conclusion : Chemical composition of saliva in diabetics in relation to healthy individuals was different Urea and Potassium level increased and Sodium level decreased.

Keywords

Saliva Chemical composition Diabetes mellitus

© 2013, Zahedan Journal of Research in Medical Sciences. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.

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