Zahedan Journal of Research in Medical Sciences

Research Article

16/8/2016

Antibacterial Activities of Bacterial Endophytes Isolated From Zataria multiflora, Achillea willhelmsii and Calendula officinalis L. Against Some Human Nosocomial Pathogens

Azam Malek Mohammadi, Azizollah Ebrahimi, Mohammad Reza Mahzonieh, Sharareh Lotfalian

Methods: In this descriptive study random samples from asymptomatic leaves and branches of three medicinal plants namely: Zataria multiflora, Achillea willhelmsii and Calendula officinalis L. were collected from Chaharmahal Va Bakhtiari province of Iran in spring 2013. For isolation of endophytic bacteria, the disinfected portions of the plants were distributed onto the isolation media. To examine endophytic bacterial contents, the bioassays were conducted with using growing colonies in peptone agar (PA) and yeast extract agar (YEA) media, then inactivated them by chloroform. To assay antibacterial activity of endophytic bacterial culture broth, filter-sterilized supernatants were poured in cylinders on each bacterial plate.

Research Article

16/8/2016

Effect of Environmental Stresses on Growth Pattern, Biofilm Formation and Biochemical Characteristics of Mycobacterium marinum CCUG20998

Mohammad Faezi Ghasemi, Mina Nasiri Moslem, Mirsasan Mirpour

Conclusions: Bacteria are able to adapt to dramatically different environments, In the case of mycobacteria, there is direct correlation between stress and pathogenicity. The results obtained from this study provided useful information on survival and tolerance of M. marinum CCUG 20998 to different environmental conditions. Survival under stress conditions might not reflect the in vivo situation where host factors also contribute to establishment of the organism during infection.

Research Article

13/8/2016

The Anti-Cancer Effect of Watercress (Rorripa Nasturtium Aquaticum) Extract on Breast Cancer Cells

Neda Fallah, Soheila Ebrahimi

Methods: In this experimental study, Watercress (Rorripa Nasturtium Aquaticum) plant were collected from Nour, Mazandaran, Iran and dried. Then the hydroalcoholic extract were obtained from dried specimen. MDA-MB-231 breast cancer cells have been treated with different concentrations of watercress extract (0 - 2 mg/mL) and after 24, 48, and 72 hours of incubation, cell viability test was performed through MTT Assay to investigate the inhibitory effect of watercress extract on cancer cells. The same test has been performed on Fibroblasts cells (HF2FF cell line) to investigate the effect of this extract on normal cells. Statistical analysis was performed using one-way analysis of variance (ANOVA method) followed by post hoc Tukey’s multiple comparisons test in SPSS 16 software.

Research Article

16/8/2016

Comparison the Effect of Zinc Oxide and Magnesium Oxide Nano Particles on Long Term Memory in Adult Male Mice

Mahnaz Kesmati, Zeinab Sargholi Notarki, Narges Issapareh, Mozhgan Torabi

Methods: In this experimental study adult male NMRI mice weighing 25 ± 3g were used. ZnO and MgO nano particles (1, 2.5 and 5 mg/kg, intrapretoneally (i.p.) were injected pre-training in model of passive avoidance learning. Memory was evaluated at 1, 3 and 7 days after training. Delay time in coming down from the safe platform in step down apparatus was evaluated as an index of memory. Open field test was used for evaluation the locomotor activity.

Research Article

10/8/2016

Determination of Relative Frequency of ABO/Rh Blood Groups in Patients with Bacteremia in Shahid Sadoughi Hospital, Yazd, Iran

Aref Atefi, Fariba Binesh, Jamshid Ayatollahi, Atefeh Atefi, Fatemeh Dehghan Mongabadi

Results: Among 100 patients with bacteremia, 48 and 52 were male and female, respectively. The patients’ mean age was 44.34 ± 31.91 years. Enterobacteriaceae (58%) and Staphylococcus aureus (27%) were the most common causes of bacteremia among these patients. In this study, Blood group A was found in 31% of patients, B in 33%, AB in 12% and O in 24%. 91% of patients were Rh positive and 9% were negative. We compared the relative frequency of blood group O with A, B and AB groups (in comparison with normal population in Yazd) and the difference was significant (P value = 0.036).

Research Article

16/8/2016

Effect of Iron Enriched Bread Intake on the Oxidative Stress Indices in Male Wistar Rats

Sharareh Heidari, Arash Omidi, Hamid Reza Gheisari, Saeed Nazifi

Methods: In this experimental study Iron, ceruloplasmin, ferritin, total iron binding capacity (TIBC), albumin, total protein, uric acid and plasma superoxide dismutase (SOD), glutathione peroxidase (GPX), catalase (CAT), malondialdehyde (MDA), and total antioxidant capacity (TAC), were evaluated in 30 rats at the first and last day of the experiment (day 30). In addition, phytic acid levels were detected in all baked breads. The data were analyzed by ANOVA and t test procedure though SPSS statistical software version 20.

Results: Serum iron level in rats that received basic level of iron plus NaHCO₃ decreased significantly in the last day of the trial. Higher level of serum iron was seen in rats that received iron twofold, fourfold and sixfold and rats that received iron fourfold plus NaHCO₃. Serum ceruloplasmin and ferritin in groups of rats that received fourfold level of iron plus NaHCO₃ and rats that received iron sixfold showed a significant increase (P ≤ 0.05). Serum total protein and uric acid in rats that received basic level of iron plus NaHCO₃ and rats that received twofold level of iron showed a significant decrease. Serum total protein levels in rats that received fourfold level of iron showed a significant decrease. Bread with NaHCO₃ showed higher phytic acid levels than other groups.

Case Report

13/8/2016

Abdominal Computed Tomography of a Fatal Amphetamine Poisoning; Pitfalls of Diagnosis and Treatment

Peyman Erfantalab, Nasim Zamani, Behrouz Hashemi-Domeneh, Hossein Hassanian-Moghaddam, Maryam Akhgri

Case Report

16/8/2016

Gradenigo Syndrome as the Form of Presentation of Nasopharyngeal

Elham Ouspid, Payam Sariaslani

Nasopharyngeal carcinoma is rare in many parts of the world, but is prevalent among Southeast Asians. Usual presenting symptoms include recurrent epistaxis, otitis media and headache. Nasopharyngeal carcinoma may also mimic Gradenigo syndrome, which consists of otitis media, facial pain in the regions innervated by the first and second divisions of trigeminal nerve and abducens nerve paralysis. In this report, we present a case which was initially diagnosed as gradenigo syndrome but turned out to be an invasive nasopharyngeal carcinoma.

Short Communication

16/8/2016

The Role of Adverse Life Style Factors in the Cause of Colorectal Carcinoma in the Residents of Yazd, Iran

Mohammad Hassan Lotfi, Naeimeh Keyghobadi, Nasimeh Javahernia, Soheila Bazm, Arefeh Dehghani Tafti, Hamid Dehghan Tezerjani

Letter

13/8/2016

Screening for Levels of 25-Hydroxyvitamin D and Levels Thyroid Hormones Among Elderly

Leila Jamshidi, Asghar Seif

Zahedan Journal of Research in Medical Sciences: Sep 2016, 18 (9), 10 articles.